Parmender P Mehta
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Explore the profile of Parmender P Mehta including associated specialties, affiliations and a list of published articles.
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17
Citations
406
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Recent Articles
1.
Ray A, Mehta P
Cell Signal
. 2021 Jun;
85:110063.
PMID: 34146657
Gap junctions (GJs) are formed by the assembly of constituent transmembrane proteins called connexins (Cxs). Aberrations in this assembly of Cxs are observed in several genetic diseases as well as...
2.
Ray A, Katoch P, Jain N, Mehta P
J Cell Sci
. 2018 Jan;
131(5).
PMID: 29361528
Defects in assembly of gap junction-forming proteins, called connexins (Cxs), are observed in a variety of cancers. Connexin32 (Cx32; also known as GJB1) is expressed by the polarized cells in...
3.
Mesnil M, Aasen T, Boucher J, Chepied A, Cronier L, Defamie N, et al.
Biochim Biophys Acta Biomembr
. 2017 Jun;
1860(1):237-243.
PMID: 28655619
This article is a report of the "International Colloquium on Gap junctions: 50Years of Impact on Cancer" that was held 8-9 September 2016, at the Amphitheater "Pôle Biologie Santé" of...
4.
Muniyan S, Chen S, Lin F, Wang Z, Mehta P, Batra S, et al.
Cell Signal
. 2015 Aug;
27(11):2261-71.
PMID: 26257301
While androgen deprivation therapy (ADT) reduces tumor burden, autocrine growth factor loops such as human epidermal growth factor receptor 2 (HER2/ErbB-2/neu) have been proposed to contribute to prostate cancer (PCa)...
5.
Katoch P, Mitra S, Ray A, Kelsey L, Roberts B, Wahl 3rd J, et al.
J Biol Chem
. 2014 Dec;
290(8):4647-4662.
PMID: 25548281
Connexins, the constituent proteins of gap junctions, are transmembrane proteins. A connexin (Cx) traverses the membrane four times and has one intracellular and two extracellular loops with the amino and...
6.
Kelsey L, Katoch P, Ray A, Mitra S, Chakraborty S, Lin M, et al.
PLoS One
. 2014 Sep;
9(9):e106437.
PMID: 25188420
1α-25(OH)2 vitamin D3 (1-25D), an active hormonal form of Vitamin D3, is a well-known chemopreventive and pro-differentiating agent. It has been shown to inhibit the growth of several prostate cancer...
7.
Johnson K, Mitra S, Katoch P, Kelsey L, Johnson K, Mehta P
Mol Biol Cell
. 2013 Feb;
24(6):715-33.
PMID: 23363606
The molecular mechanisms regulating the assembly of connexins (Cxs) into gap junctions are poorly understood. Using human pancreatic tumor cell lines BxPC3 and Capan-1, which express Cx26 and Cx43, we...
8.
Kelsey L, Katoch P, Johnson K, Batra S, Mehta P
PLoS One
. 2012 Apr;
7(4):e32846.
PMID: 22514600
The retinoids, the natural or synthetic derivatives of Vitamin A (retinol), are essential for the normal development of prostate and have been shown to modulate prostate cancer progression in vivo...
9.
Sharma N, Zheng H, Mehta P, Li Y, Patel K
Cardiovasc Res
. 2011 Aug;
92(2):348-57.
PMID: 21831995
Aims: Previously, we showed an enhanced excitatory (N-methyl d-aspartate receptor-NR(1)) and decreased inhibitory neuronal nitric oxide (NO) synthase (nNOS) influence within the paraventricular nucleus (PVN) of rats with chronic heart...
10.
Govindarajan R, Chakraborty S, Johnson K, Falk M, Wheelock M, Johnson K, et al.
Mol Biol Cell
. 2010 Oct;
21(23):4089-107.
PMID: 20881055
Cadherins have been thought to facilitate the assembly of connexins (Cxs) into gap junctions (GJs) by enhancing cell-cell contact, however the molecular mechanisms involved in this process have remained unexplored....