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Papiya Sinha

Explore the profile of Papiya Sinha including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 689
Followers 0
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Recent Articles
1.
Salzer E, Cagdas D, Hons M, Mace E, Garncarz W, Petronczki O, et al.
Nat Immunol . 2016 Nov; 17(12):1352-1360. PMID: 27776107
RASGRP1 is an important guanine nucleotide exchange factor and activator of the RAS-MAPK pathway following T cell antigen receptor (TCR) signaling. The consequences of RASGRP1 mutations in humans are unknown....
2.
Boros K, Puissant A, Back M, Alexe G, Bassil C, Sinha P, et al.
Oncotarget . 2015 Aug; 6(28):25575-87. PMID: 26315286
Recent discoveries have led to the testing of novel targeted therapies for the treatment of acute myeloid leukemia (AML). To better inform the results of clinical trials, there is a...
3.
Mace E, Dongre P, Hsu H, Sinha P, James A, Mann S, et al.
Immunol Cell Biol . 2014 Jan; 92(3):245-55. PMID: 24445602
Natural killer (NK) cell-mediated cytotoxicity is governed by the formation of a lytic immune synapse in discrete regulated steps, which give rise to an extensive array of cellular checkpoints in...
4.
Bogusz A, Baxter R, Currie T, Sinha P, Sohani A, Kutok J, et al.
Clin Cancer Res . 2012 Sep; 18(22):6122-35. PMID: 22966017
Purpose: B-cell receptor (BCR)-mediated signaling is important in the pathogenesis of a subset of diffuse large B-cell lymphomas (DLBCL) and the BCR-associated kinases SYK and BTK have recently emerged as...
5.
Shimamura T, Perera S, Foley K, Sang J, Rodig S, Inoue T, et al.
Clin Cancer Res . 2012 Jul; 18(18):4973-85. PMID: 22806877
Purpose: We describe the anticancer activity of ganetespib, a novel non-geldanamycin heat shock protein 90 (HSP90) inhibitor, in non-small cell lung cancer (NSCLC) models. Experimental Design: The activity of ganetespib...
6.
Kluk M, Chapuy B, Sinha P, Roy A, Dal Cin P, Neuberg D, et al.
PLoS One . 2012 Apr; 7(4):e33813. PMID: 22511926
Diffuse large B cell lymphoma (DLBCL) is a clinically and genetically heterogeneous disease. A small subset of DLBCLs has translocations involving the MYC locus and an additional group has a...
7.
Green M, Rodig S, Juszczynski P, Ouyang J, Sinha P, ODonnell E, et al.
Clin Cancer Res . 2012 Jan; 18(6):1611-8. PMID: 22271878
Purpose: Programmed cell death ligand 1 (PD-L1) is a molecule expressed on antigen-presenting cells that engages the PD-1 receptor on T cells and inhibits T-cell receptor signaling. The PD-1 axis...