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Paolo Innocenti

Explore the profile of Paolo Innocenti including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 1091
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Recent Articles
11.
Gao Y, van Haren M, Buijs N, Innocenti P, Zhang Y, Sartini D, et al.
J Med Chem . 2021 Aug; 64(17):12938-12963. PMID: 34424711
Nicotinamide -methyltransferase (NNMT) methylates nicotinamide (vitamin B3) to generate 1-methylnicotinamide (MNA). NNMT overexpression has been linked to a variety of diseases, most prominently human cancers, indicating its potential as a...
12.
van Groesen E, Slingerland C, Innocenti P, Mihajlovic M, Masereeuw R, Martin N
ACS Infect Dis . 2021 Aug; 7(9):2746-2754. PMID: 34387988
Vancomycin functions by binding to lipid II, the penultimate bacterial cell wall building block used by both Gram-positive and Gram-negative species. However, vancomycin is generally only able to exert its...
13.
Pignatelli P, Iezzi L, Pennese M, Raimondi P, Cichella A, Bondi D, et al.
Cancers (Basel) . 2021 Apr; 13(5). PMID: 33804585
Background: Intestinal microbiota dysbiosis may enhance the carcinogenicity of colon cancer (CC) by the proliferation and differentiation of epithelial cells. Oral () and () have the ability to invade the...
14.
DI Tommaso M, Rosa C, Caravatta L, Augurio A, Borzillo V, Di Santo S, et al.
In Vivo . 2020 May; 34(3):1223-1233. PMID: 32354913
Aim: Pathological complete response (pCR) and clinical outcomes [overall survival (OS), disease-free survival (DFS), locoregional control (LC)] were evaluated in a single-institution experience of different schedules of neoadjuvant chemoradiotherapy (CRT)...
15.
Bellenie B, Cheung K, Varela A, Pierrat O, Collie G, Box G, et al.
J Med Chem . 2020 Apr; 63(8):4047-4068. PMID: 32275432
Deregulation of the transcriptional repressor BCL6 enables tumorigenesis of germinal center B-cells, and hence BCL6 has been proposed as a therapeutic target for the treatment of diffuse large B-cell lymphoma...
16.
Anderhub S, Mak G, Gurden M, Faisal A, Drosopoulos K, Walsh K, et al.
Mol Cancer Ther . 2019 Oct; 18(10):1696-1707. PMID: 31575759
BOS172722 (CCT289346) is a highly potent, selective, and orally bioavailable inhibitor of spindle assembly checkpoint kinase MPS1. BOS172722 treatment alone induces significant sensitization to death, particularly in highly proliferative triple-negative...
17.
Woodward H, Innocenti P, Cheung K, Hayes A, Roberts J, Henley A, et al.
J Med Chem . 2018 Sep; 61(18):8226-8240. PMID: 30199249
Monopolar spindle 1 (MPS1) occupies a central role in mitosis and is one of the main components of the spindle assembly checkpoint. The MPS1 kinase is an attractive cancer target,...
18.
Napolitano L, DAlessandro V, Risio D, Marinelli C, Cianci R, Innocenti P
Ann Ital Chir . 2017 Oct; 6. PMID: 29018180
Background: A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy (SPM) has been described in literature and this association can occur either in a synchronous or...
19.
Raimondi P, Marchegiani F, Cieri M, Cichella A, Cotellese R, Innocenti P
J Robot Surg . 2017 May; 12(1):147-155. PMID: 28500580
This study analyses the utility of right colectomy as a learning procedure at the beginning of a robotic surgical program. The hypothesis is that right colectomy contains all the technical...
20.
Panaccio P, Raimondi P, Fiordaliso M, DellOsa A, Cotellese R, Innocenti P
Ann Ital Chir . 2017 Apr; 87. PMID: 28401879
Aim: Describe a rare case of intestinal obstruction due to sigmoid colon incarceration into a right Spigelian hernia and provide a literature review about its surgical management. Material Of Study:...