Paolo Cirri
Overview
Explore the profile of Paolo Cirri including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
1758
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Recent Articles
1.
Pranzini E, Muccillo L, Nesi I, Santi A, Mancini C, Lori G, et al.
Cell Death Discov
. 2024 Dec;
10(1):510.
PMID: 39706853
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of body weight occurring in about 80% of cancer patients, frequently representing the leading cause of death. Dietary intervention...
2.
Nesi I, Della Bella C, Taddei M, Santi A, Pranzini E, Paoli P, et al.
Front Oncol
. 2023 Oct;
13:1245248.
PMID: 37901327
In the early stages of carcinogenesis, the transformed cells become "invisible" to the immune system. From this moment on, the evolution of the tumor depends essentially on the genotype of...
3.
Pardella E, Pranzini E, Nesi I, Parri M, Spatafora P, Torre E, et al.
Cells
. 2022 Dec;
11(24).
PMID: 36552790
Cancer progression is supported by the cross-talk between tumor cells and the surrounding stroma. In this context, senescent cells in the tumor microenvironment contribute to the development of a pro-inflammatory...
4.
Pranzini E, Pardella E, Muccillo L, Leo A, Nesi I, Santi A, et al.
Cell Rep
. 2022 Aug;
40(7):111233.
PMID: 35977477
5-Fluorouracil (5-FU) is a key component of chemotherapy for colorectal cancer (CRC). 5-FU efficacy is established by intracellular levels of folate cofactors and DNA damage repair strategies. However, drug resistance...
5.
Genovese M, Luti S, Pardella E, Vivoli-Vega M, Pazzagli L, Parri M, et al.
Eur J Nutr
. 2022 Jan;
61(4):1905-1918.
PMID: 35066640
Purpose: The impact of tea constituents on the insulin-signaling pathway as well as their antidiabetic activity are still debated questions. Previous studies suggested that some tea components act as Protein...
6.
Leo A, Pranzini E, Pietrovito L, Pardella E, Parri M, Cirri P, et al.
Cancers (Basel)
. 2021 Jul;
13(14).
PMID: 34298765
Metastatic melanoma is characterized by poor prognosis and a low free-survival rate. Thanks to their high plasticity, melanoma cells are able to migrate exploiting different cell motility strategies, such as...
7.
Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1
Toti A, Santi A, Pardella E, Nesi I, Tomasini R, Mello T, et al.
J Cell Commun Signal
. 2021 May;
15(3):405-419.
PMID: 34021474
Cancer-associated fibroblasts (CAFs) are one of the main components of the stromal compartment in the tumor microenvironment (TME) and the crosstalk between CAFs and cancer cells is essential for tumor...
8.
PreImplantation Factor immunohistochemical expression correlates with prostate cancer aggressiveness
Raspollini M, Montagnani I, Cirri P, Baroni G, Cimadamore A, Scarpelli M, et al.
Int J Biol Markers
. 2020 May;
35(2):82-90.
PMID: 32389051
Background: The PreImplantation Factor (PIF)-a peptide secreted by viable embryos-exerts autotrophic protective effects, promotes endometrial receptivity and controls trophoblast invasion. Synthetic PIF (sPIF) has both immune-protective and regenerative properties, and...
9.
Comito G, Ippolito L, Chiarugi P, Cirri P
Front Oncol
. 2020 Apr;
10:396.
PMID: 32266157
Neoplastic tissues are composed not only by tumor cells but also by several non-transformed stromal cells, such as cancer-associated fibroblasts, endothelial and immune cells, that actively participate to tumor progression....
10.
Pranzini E, Leo A, Rapizzi E, Ramazzotti M, Magherini F, Giovannelli L, et al.
Mol Carcinog
. 2019 Aug;
58(12):2181-2192.
PMID: 31468617
Chemoresistance is the primary cause of chemotherapy failure. Compelling evidence shows that micro RNAs (miRNAs) contribute to reprogram cancer cells toward a resistant phenotype. We investigate the role of miRNAs...