Paolo Armando Gagliardi
Overview
Explore the profile of Paolo Armando Gagliardi including associated specialties, affiliations and a list of published articles.
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29
Citations
634
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Recent Articles
21.
Gagliardi P, di Blasio L, Primo L
Biochim Biophys Acta
. 2015 Aug;
1856(2):178-88.
PMID: 26238471
The ability of cells to migrate is essential for different physiological processes including embryonic development, angiogenesis, tissue repair and immune response. In the context of cancer such abilities acquire dramatic...
22.
Gagliardi P, Puliafito A, di Blasio L, Chianale F, Somale D, Seano G, et al.
Sci Rep
. 2015 May;
5:10206.
PMID: 25976978
Cellular protrusions are highly dynamic structures involved in fundamental processes, including cell migration and invasion. For a cell to migrate, its leading edge must form protrusions, and then adhere or...
23.
di Blasio L, Gagliardi P, Puliafito A, Sessa R, Seano G, Bussolino F, et al.
J Cell Sci
. 2015 Jan;
128(5):863-77.
PMID: 25588838
Non-amoeboid cell migration is characterised by dynamic competition among multiple protrusions to establish new adhesion sites at the cell's leading edge. However, the mechanisms that regulate the decision to disassemble...
24.
Seano G, Chiaverina G, Gagliardi P, di Blasio L, Puliafito A, Bouvard C, et al.
Nat Cell Biol
. 2014 Sep;
16(10):931-41, 1-8.
PMID: 25218639
The mechanism by which angiogenic endothelial cells break the physical barrier of the vascular basement membrane and consequently sprout to form new vessels in mature tissues is unclear. Here, we...
25.
Gagliardi P, di Blasio L, Puliafito A, Seano G, Sessa R, Chianale F, et al.
J Cell Biol
. 2014 Aug;
206(3):415-34.
PMID: 25092657
Directional cell migration is of paramount importance in both physiological and pathological processes, such as development, wound healing, immune response, and cancer invasion. Here, we report that 3-phosphoinositide-dependent kinase 1...
26.
Seano G, Chiaverina G, Gagliardi P, di Blasio L, Sessa R, Bussolino F, et al.
Blood
. 2013 Mar;
121(21):e129-37.
PMID: 23471306
The intrinsic complexity of the process of vessel formation limits the efficacy of cellular assays for elucidation of its molecular and pharmacologic mechanisms. We developed an ex vivo three-dimensional (3D)...
27.
Gagliardi P, di Blasio L, Orso F, Seano G, Sessa R, Taverna D, et al.
Neoplasia
. 2012 Sep;
14(8):719-31.
PMID: 22952425
3-phosphoinositide-dependent protein kinase 1 (PDK1) is the pivotal element of the phosphatidylinositol 3 kinase (PI3K) signaling pathway because it phosphorylates Akt/PKB through interactions with phosphatidylinositol 3,4,5 phosphate. Recent data indicate...
28.
Sessa R, Seano G, di Blasio L, Gagliardi P, Isella C, Medico E, et al.
Biochim Biophys Acta
. 2012 Aug;
1823(10):1925-35.
PMID: 22867989
Blood vessel formation depends on the highly coordinated actions of a variety of angiogenic regulators. Vascular endothelial growth factor (VEGF) and Angiopoietin-1 (Ang-1) are both potent and essential proangiogenic factors...
29.
Primo L, Seano G, Roca C, Maione F, Gagliardi P, Sessa R, et al.
Cancer Res
. 2010 Jun;
70(14):5759-69.
PMID: 20570893
The integrin alpha6 subunit is part of the alpha6beta1 and alpha6beta4 integrin complexes, which are known to be receptors for laminins and to mediate several biological activities such as embryogenesis,...