Paoline Laurent
Overview
Explore the profile of Paoline Laurent including associated specialties, affiliations and a list of published articles.
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14
Citations
240
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Recent Articles
1.
Garreau A, Santa P, Dubois M, Brisou D, Levionnois E, Laurent P, et al.
Eur J Immunol
. 2024 Apr;
54(6):e2350903.
PMID: 38576111
We induced systemic sclerosis (SSc)-like disease in both wild-type and Dnase1l3-deficient mice using two distinct approaches involving bleomycin and hypochlorous acid injections. Our observations revealed that the deficiency in DNASE1L3...
2.
Ah Kioon M, Laurent P, Chaudhary V, Du Y, Crow M, Barrat F
Immunol Rev
. 2024 Mar;
323(1):241-256.
PMID: 38553621
The discovery of toll-like receptors (TLRs) and the subsequent recognition that endogenous nucleic acids (NAs) could serve as TLR ligands have led to essential insights into mechanisms of healthy immune...
3.
Lee A, Laurent P, Nathan C, Barrat F
Eur J Immunol
. 2023 Dec;
54(3):e2350666.
PMID: 38161237
Mycobacterium tuberculosis (Mtb) can cause a latent infection that sometimes progresses to clinically active tuberculosis (TB). Type I interferons (IFN-I) have been implicated in initiating the progression from latency to...
4.
Cheong J, Ravishankar A, Sharma S, Parkhurst C, Grassmann S, Wingert C, et al.
Cell
. 2023 Aug;
186(18):3882-3902.e24.
PMID: 37597510
Inflammation can trigger lasting phenotypes in immune and non-immune cells. Whether and how human infections and associated inflammation can form innate immune memory in hematopoietic stem and progenitor cells (HSPC)...
5.
Laurent P, Yang C, Rendeiro A, Nilsson-Payant B, Carrau L, Chandar V, et al.
Sci Immunol
. 2022 Sep;
7(75):eadd4906.
PMID: 36083891
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients with COVID-19 by producing a cytokine storm, which correlates with increased lethality. However, these macrophages are largely not...
6.
Du Y, Ah Kioon M, Laurent P, Chaudhary V, Pierides M, Yang C, et al.
J Exp Med
. 2022 May;
219(7).
PMID: 35640018
Chemokines control the migratory patterns and positioning of immune cells to organize immune responses to pathogens. However, many chemokines have been associated with systemic autoimmune diseases that have chronic IFN...
7.
Laurent P, Lapoirie J, Leleu D, Levionnois E, Grenier C, Jurado-Mestre B, et al.
Arthritis Rheumatol
. 2021 Dec;
74(6):1013-1026.
PMID: 34962361
Objective: To characterize the role of interleukin-1β (IL-1β) and microvascular endothelial cells (MVECs) in the generation of alternatively activated macrophages in the skin, and to explore their role in the...
8.
Laurent P, Allard B, Manicki P, Jolivel V, Levionnois E, Jeljeli M, et al.
Ann Rheum Dis
. 2021 Jul;
80(12):1594-1603.
PMID: 34285051
Objective: Innate lymphoid cells-2 (ILC2) were shown to be involved in the development of lung or hepatic fibrosis. We sought to explore the functional and phenotypic heterogeneity of ILC2 in...
9.
Leleu D, Levionnois E, Laurent P, Lazaro E, Richez C, Duffau P, et al.
Front Immunol
. 2020 Nov;
11:532177.
PMID: 33193304
Background: Microparticles (MPs) are vesicular structures that derive from multiple cellular sources. MPs play important roles in intercellular communication, regulation of cell signaling or initiation of enzymatic processes. While MPs...
10.
Henrot P, Laurent P, Levionnois E, Leleu D, Pain C, Truchetet M, et al.
Front Immunol
. 2020 Oct;
11:566607.
PMID: 33117350
Systemic Sclerosis (SSc) is a complex auto-immune connective tissue disease combining inflammatory, vasculopathic and fibrotic manifestations. Skin effectively recapitulates the main pathogenic processes and therefore is a good organ to...