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Paola R Campodonico

Explore the profile of Paola R Campodonico including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 61
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Recent Articles
1.
Olavarria V, Campodonico P, Vollrath V, von Geldern P, Velasquez C, Pavez P, et al.
Lipids Health Dis . 2025 Feb; 24(1):37. PMID: 39905430
Background: The impact of a healthy diet on the secondary prevention of ischemic stroke (IS) remains uncertain. Levels of low-density lipoprotein cholesterol (LDL-C) are inversely associated with the risk of...
2.
Alcazar J, Sanchez I, Merino C, Monasterio B, Sajuria G, Miranda D, et al.
Pharmaceuticals (Basel) . 2025 Jan; 18(1). PMID: 39861158
Acute myeloid leukemia (AML) presents significant therapeutic challenges, particularly in cases driven by mutations in the FLT3 tyrosine kinase. This study aimed to develop a robust and user-friendly machine learning-based...
3.
Map Schuh C, Ezquer F, Mamani S, Campodonico P, Carcamo C, Martinez-Gomez F, et al.
Int J Pharm . 2024 Aug; 663:124553. PMID: 39103063
In chronic wound treatment, the debridement of devitalized tissue and the eradication of the biofilm must balance aggressiveness with care to protect regenerating tissues. In this study, urea, a potent...
4.
Campodonico P, Alarcon-Esposito J, Alcazar J, Olivares B, Suarez-Rozas C
Molecules . 2024 Jul; 29(14). PMID: 39064875
This study presents the potential role of deep eutectic solvents (DESs) in a lipase-catalyzed hydrolysis reaction as a co-solvent in an aqueous solution given by a phosphate buffer. Ammonium salts,...
5.
Campodonico P, Calderon C, Alcazar J, Olivares B, Jaldin L, Suarez-Rozas C
Front Chem . 2024 Jan; 11:1289398. PMID: 38268763
The performance of lipase B (CALB) has been evaluated in 1-butyl-3-methylimidazolium tetrafluoroborate (BMIMBF)/water mixtures in a wide range of molar fractions () with and without 1-dodecyl-3-methylimidazolium tetrafluoroborate (C-MIMBF), a surfactant...
6.
Alcazar J, Misad Saide A, Campodonico P
J Cheminform . 2023 Sep; 15(1):90. PMID: 37770903
This article presents a quantitative structure-activity relationship (QSAR) approach for predicting the acid dissociation constant (pK) of nitrogenous compounds, including those within supramolecular complexes based on cucurbiturils. The model combines...
7.
Geue N, Alcazar J, Campodonico P
Molecules . 2023 Mar; 28(6). PMID: 36985598
Understanding the non-covalent interactions in host-guest complexes is crucial to their stability, design and applications. Here, we use density functional theory to compare the ability of β-cyclodextrin () and heptakis(2,6-di-O-methyl)-β-cyclodextrin...
8.
Campodonico P, Alarcon-Esposito J, Olivares B
Front Chem . 2022 Jun; 10:854918. PMID: 35755252
Few kinetic parameters, or reaction rates, are known up to date in detail about 1-chloro and 1-fluoro-2,4-dinitrobenzene (ClDNB and FDNB, respectively) with a series of biothiols in aqueous media. These...
9.
Sanchez B, Campodonico P, Contreras R
Front Chem . 2022 Apr; 10:861379. PMID: 35433634
An experimental and computational methodology for the analysis of the Lewis acid/base responses of ionic liquids (ILs) and deep eutectic solvents (DES) is proposed. It is based on the donor...
10.
Campodonico P, Tapia R, Suarez-Rozas C
Front Chem . 2022 Feb; 9:740161. PMID: 35186890
The reactions between 2-chloro-5-nitro pyrimidine with a serie of α-nucleophile derivatives were kinetically evaluated. The kinetic study was carried out in aqueous media and the data shown an unusual split...