Pang-Hsien Tu
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Explore the profile of Pang-Hsien Tu including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
1333
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Recent Articles
11.
Wu H, Lin Y, Liu C, Chung H, Wang Y, Lin Y, et al.
Nat Commun
. 2014 Feb;
5:3214.
PMID: 24487962
The promyelocytic leukaemia (PML) protein controls multiple tumour suppressive functions and is downregulated in diverse types of human cancers through incompletely characterized post-translational mechanisms. Here we identify USP11 as a...
12.
Huang Y, Lin K, He R, Tu P, Koubek J, Hsu Y, et al.
PLoS One
. 2013 Jun;
8(5):e64002.
PMID: 23737961
The aggregation of TAR DNA-binding protein (TDP-43) has been shown as a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) since 2006. While evidence has suggested that...
13.
Soong B, Liao Y, Tu P, Tsai P, Lee I, Chung C, et al.
J Chin Med Assoc
. 2013 Apr;
76(6):319-24.
PMID: 23602593
Background: Mutations in the TREX1 and NOTCH3 genes cause retinal vasculopathy with cerebral leukodystrophy (RVCL) and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), respectively. Both are hereditary...
14.
Wang Y, Lin K, Chen S, Gu D, Chen C, Tu P, et al.
Hepatology
. 2013 Mar;
58(1):239-50.
PMID: 23460382
Unlabelled: Eukaryotic translation initiation factor 3 subunit I (eIF3I) with transforming capability is often overexpressed in human hepatocellular carcinoma (HCC) but its oncogenic mechanisms remain unknown. We demonstrate that eIF3I...
15.
Soong B, Huang Y, Tsai P, Huang C, Pan H, Lu Y, et al.
Am J Hum Genet
. 2013 Feb;
92(3):422-30.
PMID: 23434117
Charcot-Marie-Tooth disease (CMT) is a heterogeneous group of inherited neuropathies. Mutations in approximately 45 genes have been identified as being associated with CMT. Nevertheless, the genetic etiologies of at least...
16.
Hsiao H, Chen Y, Chen H, Tu P, Chern Y
Hum Mol Genet
. 2013 Feb;
22(9):1826-42.
PMID: 23372043
Huntington's disease (HD) is an autosomal disease caused by a CAG repeat expansion in the huntingtin (HTT) gene. The resultant mutant HTT protein (mHTT) forms aggregates in various types of...
17.
Tsai C, Soong B, Tu P, Lin K, Fuh J, Tsai P, et al.
Neurobiol Aging
. 2012 Jun;
33(9):2232.e11-2232.e18.
PMID: 22673113
A GGGGCC hexanucleotide repeat expansion in the C9ORF72 gene was recently identified as an important cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia in Caucasian populations. The role...
18.
Lo W, Chu P, Lee T, Su T, Chien Y, Chen Y, et al.
Int J Mol Sci
. 2012 Apr;
13(3):3277-3290.
PMID: 22489152
Although surgery or the combination of chemotherapy and radiation are reported to improve the quality of life and reduce symptoms in patients with oral cancer, the prognosis of oral cancer...
19.
Hsieh M, Ho J, Lin L, Tu P, Perry A, Huang A
Clin Neurol Neurosurg
. 2012 Mar;
114(7):1027-9.
PMID: 22397971
No abstract available.
20.
Chen L, Chu P, Lee Y, Tu P, Chi C, Lee H, et al.
Int J Mol Sci
. 2012 Feb;
13(1):1209-1224.
PMID: 22312313
Autophagy is activated by various stresses, including DNA damage, and previous studies of DNA damage-induced autophagy have focused on the response to chemotherapeutic drugs, ionizing radiation, and reactive oxygen species....