Pamela C L Ferreira
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Explore the profile of Pamela C L Ferreira including associated specialties, affiliations and a list of published articles.
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28
Citations
359
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Recent Articles
11.
Macedo A, Therriault J, Tissot C, Fernandez-Arias J, Ferreira P, Vitali P, et al.
Brain Commun
. 2024 Mar;
6(2):fcae043.
PMID: 38482373
The progression of PET-based Braak stages correlates with cognitive deterioration in aging and Alzheimer's disease. Here, we investigate the association between PET-based Braak stages and functional impairment and assess whether...
12.
Ferrari-Souza J, Brum W, Hauschild L, Da Ros L, Ferreira P, Bellaver B, et al.
Neurobiol Aging
. 2024 Feb;
136:88-98.
PMID: 38335912
Understanding whether vascular risk factors (VRFs) synergistically potentiate Alzheimer's disease (AD) progression is important in the context of emerging treatments for preclinical AD. In a group of 503 cognitively unimpaired...
13.
Schaffer Aguzzoli C, Ferreira P, Povala G, Ferrari-Souza J, Bellaver B, Soares Katz C, et al.
JAMA Netw Open
. 2023 Nov;
6(11):e2345175.
PMID: 38010651
Importance: Neuropsychiatric symptoms are commonly encountered and are highly debilitating in patients with Alzheimer disease. Understanding their underpinnings has implications for identifying biomarkers and treatment for these symptoms. Objective: To...
14.
Gonzalez-Ortiz F, Ferreira P, Gonzalez-Escalante A, Montoliu-Gaya L, Ortiz-Romero P, Kac P, et al.
Alzheimers Dement
. 2023 Nov;
20(2):1239-1249.
PMID: 37975513
Introduction: Detection of Alzheimer's disease (AD) pathophysiology among individuals with mild cognitive changes and those experiencing subjective cognitive decline (SCD) remains challenging. Plasma phosphorylated tau 217 (p-tau217) is one of...
15.
Gonzalez-Ortiz F, Ferreira P, Gonzalez A, Montoliu-Gaya L, Ortiz-Romero P, Kac P, et al.
medRxiv
. 2023 Oct;
PMID: 37873312
Introduction: Detection of Alzheimer's disease (AD) pathophysiology among cognitively unimpaired individuals and those experiencing subjective cognitive decline (SCD) remains challenging. Plasma p-tau217 is one of the most promising of the...
16.
Ferrari-Souza J, Bellaver B, Ferreira P, Benedet A, Povala G, Lussier F, et al.
Nat Aging
. 2023 Sep;
3(10):1210-1218.
PMID: 37749258
The mechanisms by which the apolipoprotein E ε4 (APOEε4) allele influences the pathophysiological progression of Alzheimer's disease (AD) are poorly understood. Here we tested the association of APOEε4 carriership and...
17.
Ferreira P, Therriault J, Tissot C, Ferrari-Souza J, Benedet A, Povala G, et al.
Alzheimers Dement
. 2023 Aug;
19(10):4463-4474.
PMID: 37534889
Introduction: Phosphorylated tau (p-tau) biomarkers have been recently proposed to represent brain amyloid-β (Aβ) pathology. Here, we evaluated the plasma biomarkers' contribution beyond the information provided by demographics (age and...
18.
Carello-Collar G, Bellaver B, Ferreira P, Ferrari-Souza J, Ramos V, Therriault J, et al.
Mol Psychiatry
. 2023 Jul;
28(12):5025-5036.
PMID: 37419974
The γ-aminobutyric acid (GABA)ergic system is the primary inhibitory neurotransmission system in the mammalian brain. Its dysregulation has been shown in multiple brain conditions, but in Alzheimer's disease (AD) studies...
19.
Bellaver B, Povala G, Ferreira P, Ferrari-Souza J, Leffa D, Lussier F, et al.
Nat Med
. 2023 May;
29(7):1775-1781.
PMID: 37248300
An unresolved question for the understanding of Alzheimer's disease (AD) pathophysiology is why a significant percentage of amyloid-β (Aβ)-positive cognitively unimpaired (CU) individuals do not develop detectable downstream tau pathology...
20.
Ferrari-Souza J, Lussier F, Leffa D, Therriault J, Tissot C, Bellaver B, et al.
Sci Adv
. 2023 Apr;
9(14):eade1474.
PMID: 37018391
Animal studies suggest that the apolipoprotein E ε4 (ε4) allele is a culprit of early microglial activation in Alzheimer's disease (AD). Here, we tested the association between ε4 status and...