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Pamela Bakirci

Explore the profile of Pamela Bakirci including associated specialties, affiliations and a list of published articles. Areas
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Citations 127
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Recent Articles
1.
Goniotaki D, Lakkaraju A, Shrivastava A, Bakirci P, Sorce S, Senatore A, et al.
PLoS Pathog . 2017 Nov; 13(11):e1006733. PMID: 29176838
Prion infections cause inexorable, progressive neurological dysfunction and neurodegeneration. Expression of the cellular prion protein PrPC is required for toxicity, suggesting the existence of deleterious PrPC-dependent signaling cascades. Because group-I...
2.
Kuffer A, Lakkaraju A, Mogha A, Petersen S, Airich K, Doucerain C, et al.
Nature . 2016 Aug; 536(7617):464-8. PMID: 27501152
Ablation of the cellular prion protein PrP(C) leads to a chronic demyelinating polyneuropathy affecting Schwann cells. Neuron-restricted expression of PrP(C) prevents the disease, suggesting that PrP(C) acts in trans through...