Palak C Genge
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Explore the profile of Palak C Genge including associated specialties, affiliations and a list of published articles.
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9
Citations
134
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Recent Articles
1.
Heubeck A, Phalen C, Kaul N, Wittig P, Garber J, Weiss M, et al.
J Transl Med
. 2025 Jan;
23(1):5.
PMID: 39754129
Background: The field of single cell technologies has rapidly advanced our comprehension of the human immune system, offering unprecedented insights into cellular heterogeneity and immune function. While cryopreserved peripheral blood...
2.
He Z, Glass M, Venkatesan P, Feser M, Lazaro L, Okada L, et al.
bioRxiv
. 2024 Nov;
PMID: 39554042
Some autoimmune diseases, including rheumatoid arthritis (RA), are preceded by a critical subclinical phase of disease activity. Proactive clinical management is hampered by a lack of biological understanding of this...
3.
Gong Q, Sharma M, Kuan E, Glass M, Chander A, Singh M, et al.
bioRxiv
. 2024 Sep;
PMID: 39314416
The generation and maintenance of protective immunity is a dynamic interplay between host and environment that is impacted by age. Understanding fundamental changes in the healthy immune system that occur...
4.
Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim S, et al.
Nat Immunol
. 2024 Jan;
25(3):577.
PMID: 38267693
No abstract available.
5.
Thomson Z, He Z, Swanson E, Henderson K, Phalen C, Zaim S, et al.
Nat Immunol
. 2023 Oct;
24(11):1947-1959.
PMID: 37845489
Age-associated changes in the T cell compartment are well described. However, limitations of current single-modal or bimodal single-cell assays, including flow cytometry, RNA-seq (RNA sequencing) and CITE-seq (cellular indexing of...
6.
Genge P, Roll C, Heubeck A, Swanson E, Kondza N, Lord C, et al.
STAR Protoc
. 2021 Nov;
2(4):100900.
PMID: 34806044
Deep immune profiling is essential for understanding the human immune system in health and disease. Successful biological interpretation of this data requires consistent laboratory processing with minimal batch-to-batch variation. Here,...
7.
Savage A, Gutschow M, Chiang T, Henderson K, Green R, Chaudhari M, et al.
iScience
. 2021 Jun;
24(5):102404.
PMID: 34113805
Multi-omic profiling of human peripheral blood is increasingly utilized to identify biomarkers and pathophysiologic mechanisms of disease. The importance of these platforms in clinical and translational studies led us to...
8.
Talla A, Vasaikar S, Lemos M, Moodie Z, Lee Pebworth M, Henderson K, et al.
bioRxiv
. 2021 Jun;
PMID: 34075380
SARS-CoV-2 has infected over 200 million and caused more than 4 million deaths to date. Most individuals (>80%) have mild symptoms and recover in the outpatient setting, but detailed studies...
9.
Swanson E, Lord C, Reading J, Heubeck A, Genge P, Thomson Z, et al.
Elife
. 2021 Apr;
10.
PMID: 33835024
Single-cell measurements of cellular characteristics have been instrumental in understanding the heterogeneous pathways that drive differentiation, cellular responses to signals, and human disease. Recent advances have allowed paired capture of...