Pal Mikecz
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Explore the profile of Pal Mikecz including associated specialties, affiliations and a list of published articles.
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22
Citations
89
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Recent Articles
1.
Nemeth E, Gyuricza B, Forgacs V, Cumming P, Henriksen G, Marton J, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685958
We have established a method for nucleophilic one-pot, two-step radiosynthesis of the popular opioid receptor radioligand 6--(2-[F]fluoroethyl)-6--desmethyl-diprenorphine ([F]FE-DPN) from the novel precursor 6--(2-tosyloxyethyl)-6--desmethyl- 3--trityl-diprenorphine (TE-TDDPN), which we designate as the...
2.
Marton J, Fekete A, Cumming P, Hosztafi S, Mikecz P, Henriksen G
Molecules
. 2022 May;
27(9).
PMID: 35566212
6,14-ethenomorphinans are semisynthetic opiate derivatives containing an ethylene bridge between positions 6 and 14 in ring-C of the morphine skeleton that imparts a rigid molecular structure. These compounds represent an...
3.
Forgacs V, Nemeth E, Gyuricza B, Kis A, Szabo J, Mikecz P, et al.
ChemMedChem
. 2020 Sep;
15(24):2470-2476.
PMID: 32935925
The radiosynthesis, as well as the in vivo and ex vivo biodistribution of the C radiolabelled 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime (6, [ C]SZV 1287) are reported. SZV 1287 is a novel semicarbazide-sensitive...
4.
Mikecz P, Fekete A, Toth G, Kornyei J, Bali T, Cservenyak T, et al.
Magy Onkol
. 2020 Jun;
64(2):104-111.
PMID: 32520003
"PET based" molecular imaging has significant role in personalized medicine. New radiopharmaceuticals are continuously introduced into the daily practice of detecting diseases and assessing the effectiveness of therapy. In recent...
5.
Kornyei J, Mikecz P, Toth G
Magy Onkol
. 2014 Dec;
58(4):245-50.
PMID: 25517442
18F-fluoro-deoxyglucose (FDG) can be considered as the "work-horse" of PET/CT and PET/MR imaging modalities. FDG provides insight in the pathophysiology of tumors and metastases from the point of view of...
6.
Trencsenyi G, Marian T, Lajtos I, Krasznai Z, Balkay L, Emri M, et al.
Biomed Res Int
. 2014 Oct;
2014:787365.
PMID: 25309926
Expression of multidrug pumps including P-glycoprotein (MDR1, ABCB1) in the plasma membrane of tumor cells often results in decreased intracellular accumulation of anticancer drugs causing serious impediment to successful chemotherapy....
7.
Krasznai Z, Trencsenyi G, Krasznai Z, Mikecz P, Nizsaloczki E, Szaloki G, et al.
Eur J Pharm Sci
. 2014 Aug;
64:1-8.
PMID: 25149126
2-[(18)F]fluoro-2-deoxy-d-glucose ((18)FDG) is a tumor diagnostic radiotracer of great importance in both diagnosing primary and metastatic tumors and in monitoring the efficacy of the treatment. P-glycoprotein (Pgp) is an active...
8.
Krasznai Z, Toth A, Mikecz P, Fodor Z, Szabo G, Galuska L, et al.
Eur J Pharm Sci
. 2010 Sep;
41(5):665-9.
PMID: 20869436
P-glycoprotein (Pgp, ABCB1) is one of the active efflux pumps that are able to extrude a large variety of chemotherapeutic drugs from the cells, causing the phenomenon of multidrug resistance....
9.
Gyongyosi M, Hemetsberger R, Wolbank S, Kaun C, Posa A, Marian T, et al.
JACC Cardiovasc Imaging
. 2010 Jul;
3(7):772-5.
PMID: 20633856
No abstract available.
10.
Mikecz P, Marian T, Miklovicz T, Galuska L, Krasznai Z, Toth A, et al.
Appl Radiat Isot
. 2009 Aug;
67(10):1806-11.
PMID: 19674913
We studied how very short (10-40min) incubation with anthracycline derivatives modifies the accumulation of PET tumor-diagnostic radiotracers in cancer cells. The human ovarian A2780 and A2780AD, human B lymphoid JY,...