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Pacita L Roberts

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Articles 16
Citations 972
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Recent Articles
1.
Hooton T, Roberts P, Stapleton A
Clin Infect Dis . 2020 Mar; 72(8):1332-1338. PMID: 32179902
Background: Asymptomatic bacteriuria and pyuria in healthy women often trigger inappropriate antimicrobial treatment, but there is a paucity of data on their prevalence and persistence. Methods: To evaluate the prevalence...
2.
Schreiber 4th H, Conover M, Chou W, Hibbing M, Manson A, Dodson K, et al.
Sci Transl Med . 2017 Mar; 9(382). PMID: 28330863
Urinary tract infections (UTIs) are caused by uropathogenic (UPEC) strains. In contrast to many enteric pathogroups, no genetic signature has been identified for UPEC strains. We conducted a high-resolution comparative...
3.
Hannan T, Roberts P, Riehl T, van Der Post S, Binkley J, Schwartz D, et al.
EBioMedicine . 2015 Jul; 1(1):46-57. PMID: 26125048
The spread of multidrug-resistant microorganisms globally has created an urgent need for novel therapeutic strategies to combat urinary tract infections (UTIs). Immunomodulatory therapy may provide benefit, as treatment of mice...
4.
Stapleton A, Cox M, DiNello R, Geisberg M, Abbott A, Roberts P, et al.
J Clin Microbiol . 2015 Jun; 53(9):2805-9. PMID: 26063858
Urinary tract infections (UTIs) are frequently encountered in clinical practice and most commonly caused by Escherichia coli and other Gram-negative uropathogens. We tested RapidBac, a rapid immunoassay for bacteriuria developed...
5.
Steigedal M, Marstad A, Haug M, Damas J, Strong R, Roberts P, et al.
J Immunol . 2014 Nov; 193(12):6081-9. PMID: 25398327
Competition for iron is a critical component of successful bacterial infections, but the underlying in vivo mechanisms are poorly understood. We have previously demonstrated that lipocalin 2 (LCN2) is an...
6.
Hooton T, Roberts P, Cox M, Stapleton A
N Engl J Med . 2013 Nov; 369(20):1883-91. PMID: 24224622
Background: The cause of acute uncomplicated cystitis is determined on the basis of cultures of voided midstream urine, but few data guide the interpretation of such results, especially when gram-positive...
7.
Tchesnokova V, Billig M, Chattopadhyay S, Linardopoulou E, Aprikian P, Roberts P, et al.
J Clin Microbiol . 2013 Jul; 51(9):2991-9. PMID: 23843485
The ability to identify bacterial pathogens at the subspecies level in clinical diagnostics is currently limited. We investigated whether splitting Escherichia coli species into clonal groups (clonotypes) predicts antimicrobial susceptibility...
8.
Johnson J, Tchesnokova V, Johnston B, Clabots C, Roberts P, Billig M, et al.
J Infect Dis . 2013 Jan; 207(6):919-28. PMID: 23288927
Background: Fluoroquinolone-resistant Escherichia coli are increasingly prevalent. Their clonal origins--potentially critical for control efforts--remain undefined. Methods: Antimicrobial resistance profiles and fine clonal structure were determined for 236 diverse-source historical (1967-2009)...
9.
Hooton T, Roberts P, Stapleton A
JAMA . 2012 Feb; 307(6):583-9. PMID: 22318279
Context: Although fluoroquinolones remain the most reliable urinary antimicrobial, resistance rates have increased and effective fluoroquinolone-sparing antimicrobials are needed. Objective: To determine whether cefpodoxime is noninferior to ciprofloxacin for treatment...
10.
Stapleton A, Au-Yeung M, Hooton T, Fredricks D, Roberts P, Czaja C, et al.
Clin Infect Dis . 2011 Apr; 52(10):1212-7. PMID: 21498386
Background: Urinary tract infections (UTIs) are common among women and frequently recur. Depletion of vaginal lactobacilli is associated with UTI risk, which suggests that repletion may be beneficial. We conducted...