Pablo Lopez-Jimenez
Overview
Explore the profile of Pablo Lopez-Jimenez including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
74
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Recent Articles
1.
Lopez-Jimenez P, Berenguer I, Perez-Moreno I, de Aledo J, Parra M, Page J, et al.
Methods Mol Biol
. 2024 Aug;
2818:147-160.
PMID: 39126472
Male mouse meiosis has been traditionally studied using descriptive methods like histological sections and spreading or squashing techniques, which allow the observation of fixed meiocytes in either wildtype or genetically...
2.
Skinner M, Simington C, Lopez-Jimenez P, Baran K, Xu J, Dayani Y, et al.
EMBO Rep
. 2024 Jun;
25(8):3373-3405.
PMID: 38943004
Centrosomes are the canonical microtubule organizing centers (MTOCs) of most mammalian cells, including spermatocytes. Centrosomes comprise a centriole pair within a structurally ordered and dynamic pericentriolar matrix (PCM). Unlike in...
3.
Castellano-Pozo M, Sioutas G, Barroso C, Prince J, Lopez-Jimenez P, Davy J, et al.
Elife
. 2023 Aug;
12.
PMID: 37650378
The cohesin complex plays essential roles in chromosome segregation, 3D genome organisation, and DNA damage repair through its ability to modify DNA topology. In higher eukaryotes, meiotic chromosome function, and...
4.
Valero-Regalon F, Sole M, Lopez-Jimenez P, Valerio-de Arana M, Martin-Ruiz M, de la Fuente R, et al.
Front Cell Dev Biol
. 2023 May;
11:1147610.
PMID: 37181752
In eutherian mammals, hundreds of programmed DNA double-strand breaks (DSBs) are generated at the onset of meiosis. The DNA damage response is then triggered. Although the dynamics of this response...
5.
Lopez-Jimenez P, Perez-Martin S, Hidalgo I, Garcia-Gonzalo F, Page J, Gomez R
Cells
. 2023 Jan;
12(1).
PMID: 36611937
Cilia are hair-like projections of the plasma membrane with an inner microtubule skeleton known as axoneme. Motile cilia and flagella beat to displace extracellular fluids, playing important roles in the...
6.
Berenguer I, Lopez-Jimenez P, Mena I, Viera A, Page J, Gonzalez-Martinez J, et al.
J Cell Sci
. 2022 Jun;
135(13).
PMID: 35694956
Chromosome segregation requires that centromeres properly attach to spindle microtubules. This essential step regulates the accuracy of cell division and must therefore be precisely regulated. One of the main centromeric...
7.
Gil-Fernandez A, Ribagorda M, Martin-Ruiz M, Lopez-Jimenez P, Laguna T, Gomez R, et al.
Genes (Basel)
. 2021 Sep;
12(9).
PMID: 34573416
X and Y chromosomes in mammals are different in size and gene content due to an evolutionary process of differentiation and degeneration of the Y chromosome. Nevertheless, these chromosomes usually...
8.
de la Fuente R, Pratto F, Hernandez-Hernandez A, Manterola M, Lopez-Jimenez P, Gomez R, et al.
Cells
. 2021 Sep;
10(9).
PMID: 34571960
Meiosis involves a series of specific chromosome events, namely homologous synapsis, recombination, and segregation. Disruption of either recombination or synapsis in mammals results in the interruption of meiosis progression during...
9.
Perez-Garcia V, Lea G, Lopez-Jimenez P, Okkenhaug H, Burton G, Moffett A, et al.
Elife
. 2021 Jun;
10.
PMID: 34170818
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified the...
10.
Alfaro E, Lopez-Jimenez P, Gonzalez-Martinez J, Malumbres M, Suja J, Gomez R
EMBO Rep
. 2021 Feb;
22(4):e51030.
PMID: 33615693
Cell division requires the regulation of karyokinesis and cytokinesis, which includes an essential role of the achromatic spindle. Although the functions of centrosomes are well characterised in somatic cells, their...