Pablo Javier Espejo
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Explore the profile of Pablo Javier Espejo including associated specialties, affiliations and a list of published articles.
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8
Citations
54
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Recent Articles
1.
Champarini L, Herrera M, Comas Mutis R, Espejo P, Molina V, Calfa G, et al.
Hippocampus
. 2022 Aug;
32(10):765-775.
PMID: 36000813
Growth factors, such as insulin-like growth factor 1 (IGF-1), among others are known for their critical involvement in learning and memory processes. IGF-1 regulates cognitive functions, synapse density, neurotransmission, and...
2.
Comas Mutis R, Espejo P, Martijena I, Molina V, Calfa G
Hippocampus
. 2021 Jun;
31(10):1080-1091.
PMID: 34190369
Reconsolidation of a contextual fear memory is a protein synthesis-dependent process in which a previously destabilized memory returns to a stable state. This process has become the subject of many...
3.
Espejo P, Ortiz V, Martijena I, Molina V
Neurobiol Learn Mem
. 2021 Jan;
179:107386.
PMID: 33476748
The destabilization/reconsolidation process can be triggered by memory recall, allowing consolidated memories to be modified. We have previously reported that stress prior to fear conditioning induces memories that exhibit resistance...
4.
de Sa Couto-Pereira N, Lampert C, Vieira A, Lazzaretti C, Kincheski G, Espejo P, et al.
Front Mol Neurosci
. 2019 Jun;
12:134.
PMID: 31191245
Early life experiences program lifelong responses to stress. In agreement, resilience and vulnerability to psychopathologies, such as posttraumatic stress disorder (PTSD), have been suggested to depend on the early background....
5.
Ortiz V, Espejo P, Molina V, Martijena I
Prog Neuropsychopharmacol Biol Psychiatry
. 2018 Aug;
89:9-15.
PMID: 30145183
A 1-day fear memory in ethanol withdrawn (ETOH) rats is resistant to destabilization-reconsolidation process. However, d-cycloserine (DCS) reverts this disturbance. Considering that the formation of pathological fear memories in humans...
6.
Espejo P, Ortiz V, Martijena I, Molina V
Neurobiol Learn Mem
. 2017 Jul;
144:166-173.
PMID: 28669783
It is well known that stress can affect mnemonic processes. In particular, stress before contextual fear conditioning induces a memory which exhibits resistance to being interfered with by Midazolam (MDZ)...
7.
Espejo P, Ortiz V, Martijena I, Molina V
Neuropharmacology
. 2016 Jul;
109:349-356.
PMID: 27378335
Consolidated memories can enter into a labile state after reactivation followed by a restabilization process defined as reconsolidation. This process can be interfered with Midazolam (MDZ), a positive allosteric modulator...
8.
Ortiz V, Giachero M, Espejo P, Molina V, Martijena I
Int J Neuropsychopharmacol
. 2015 Jan;
18(4).
PMID: 25617327
Background: Withdrawal from chronic ethanol facilitates the formation of contextual fear memory and delays the onset to extinction, with its retrieval promoting an increase in ethanol consumption. Consequently, manipulations aimed...