Irene Delia Martijena
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Explore the profile of Irene Delia Martijena including associated specialties, affiliations and a list of published articles.
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11
Citations
70
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Recent Articles
1.
Comas Mutis R, Espejo P, Martijena I, Molina V, Calfa G
Hippocampus
. 2021 Jun;
31(10):1080-1091.
PMID: 34190369
Reconsolidation of a contextual fear memory is a protein synthesis-dependent process in which a previously destabilized memory returns to a stable state. This process has become the subject of many...
2.
Espejo P, Ortiz V, Martijena I, Molina V
Neurobiol Learn Mem
. 2021 Jan;
179:107386.
PMID: 33476748
The destabilization/reconsolidation process can be triggered by memory recall, allowing consolidated memories to be modified. We have previously reported that stress prior to fear conditioning induces memories that exhibit resistance...
3.
Ortiz V, Calfa G, Molina V, Martijena I
Prog Neuropsychopharmacol Biol Psychiatry
. 2019 Apr;
93:197-204.
PMID: 30978427
Fear memory reactivation does not always lead to memory destabilization-reconsolidation. For instance, fear memories formed following withdrawal from chronic ethanol consumption or a stressful event are less likely to become...
4.
Ortiz V, Espejo P, Molina V, Martijena I
Prog Neuropsychopharmacol Biol Psychiatry
. 2018 Aug;
89:9-15.
PMID: 30145183
A 1-day fear memory in ethanol withdrawn (ETOH) rats is resistant to destabilization-reconsolidation process. However, d-cycloserine (DCS) reverts this disturbance. Considering that the formation of pathological fear memories in humans...
5.
Espejo P, Ortiz V, Martijena I, Molina V
Neurobiol Learn Mem
. 2017 Jul;
144:166-173.
PMID: 28669783
It is well known that stress can affect mnemonic processes. In particular, stress before contextual fear conditioning induces a memory which exhibits resistance to being interfered with by Midazolam (MDZ)...
6.
Ortiz V, Molina V, Martijena I
Behav Brain Res
. 2016 Aug;
315:66-70.
PMID: 27522017
The pharmacological blockade of memory reconsolidation has been suggested as a potential treatment to the attenuation of maladaptive memories associated to psychiatric disorders and drug addiction. To interfere with the...
7.
Espejo P, Ortiz V, Martijena I, Molina V
Neuropharmacology
. 2016 Jul;
109:349-356.
PMID: 27378335
Consolidated memories can enter into a labile state after reactivation followed by a restabilization process defined as reconsolidation. This process can be interfered with Midazolam (MDZ), a positive allosteric modulator...
8.
Ortiz V, Giachero M, Espejo P, Molina V, Martijena I
Int J Neuropsychopharmacol
. 2015 Jan;
18(4).
PMID: 25617327
Background: Withdrawal from chronic ethanol facilitates the formation of contextual fear memory and delays the onset to extinction, with its retrieval promoting an increase in ethanol consumption. Consequently, manipulations aimed...
9.
Maldonado N, Martijena I, Molina V
Behav Brain Res
. 2011 Jul;
225(1):77-84.
PMID: 21763355
It is well known that an emotionally arousing experience usually results in a robust and persistent memory trace. The present study explored the potential mechanisms involved in the influence of...
10.
Bertotto M, Maldonado N, Bignante E, Gorosito S, Cambiasso M, Molina V, et al.
Eur Neuropsychopharmacol
. 2011 Feb;
21(12):892-904.
PMID: 21315561
The extracellular signal-regulated kinase (ERK) pathway, which can be activated by NMDA receptor stimulation, is involved in fear conditioning and drug addiction. We have previously shown that withdrawal from chronic...