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Pablo Ferreira das Chagas

Explore the profile of Pablo Ferreira das Chagas including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Martins-da-Silva A, Baroni M, Salomao K, das Chagas P, Bonfim-Silva R, Geron L, et al.
Cell Mol Neurobiol . 2022 Apr; 43(2):813-826. PMID: 35366170
Medulloblastoma is the most common type of pediatric malignant primary brain tumor, and about one-third of patients die due to disease recurrence and most survivors suffer from long-term side effects....
2.
Cruzeiro G, de Almeida Magalhaes T, de Sousa G, Bonfim Silva R, de Biagi Junior C, das Chagas P, et al.
Cancers (Basel) . 2021 Dec; 13(24). PMID: 34944872
Advances in genomics have led to the identification of twelve relevant molecular subtypes within medulloblastoma (MB). The alpha subtype of Sonic hedgehog-driven MB is resistant to therapy (including smoothened inhibitors)...
3.
das Chagas P, de Sousa G, Veronez L, Martins-da-Silva A, Correa C, Cruzeiro G, et al.
J Mol Neurosci . 2021 Nov; 72(3):633-641. PMID: 34822110
The Group 3 Medulloblastoma (Grp3-MB) is an aggressive molecular subtype with a high incidence of metastasis and deaths. In this study, were used an RNA sequencing data (RNA-Seq) from a...
4.
de Sousa G, Vieira G, das Chagas P, Pezuk J, Brassesco M
Pharmacol Res . 2020 Jul; 160:105093. PMID: 32726671
Cancer targeted therapy, either alone or in combination with conventional chemotherapy, could allow the survival of patients with neoplasms currently considered incurable. In recent years, the dysregulation of the Rho-associated...
5.
Feitosa J, das Chagas P, de Sousa G, Queiroz R, Cruzeiro G, Tone L, et al.
Mol Biol Rep . 2020 Jul; 47(8):6439-6443. PMID: 32671623
TP53 p.R337H germline mutation is highly prevalent in the Southern region of Brazil. We sought to investigate TP53 p.R337H mutation in pediatric tumor samples from a population settled in a...
6.
Dos Santos Klinger P, Delsin L, Cruzeiro G, Andrade A, Lira R, Andrade P, et al.
Sci Rep . 2020 Apr; 10(1):6836. PMID: 32321992
We evaluated the potential effects of ATO in different pediatric SHH-MB cell lines (ONS-76: TP53-wild type; DAOY and UW402: TP53-mutated). MB cell lines molecular subgroup was confirmed and TP53 mutations...
7.
das Chagas P, de Sousa G, Kodama M, de Biagi Junior C, Yunes J, Brandalise S, et al.
Hematol Transfus Cell Ther . 2020 Feb; 43(1):28-34. PMID: 32014474
Aberrant expression of long non-coding RNAs (lncRNAs) has been detected in several types of cancer, including acute lymphoblastic leukemia (ALL), but lncRNA mapped on transcribed ultraconserved regions (T-UCRs) are little...
8.
das Chagas P, Baroni M, Brassesco M, Tone L
J Gene Med . 2019 Nov; 22(1):e3136. PMID: 31692135
Musashi comprises an evolutionarily conserved family of RNA-binding proteins (RBP) that regulate cell fate decisions during embryonic development and play key roles in the maintenance of self-renewal and differentiation of...
9.
Falci S, Teixeira M, das Chagas P, Martinez B, Loyola A, Ferreira L, et al.
Acta Cir Bras . 2015 Aug; 30(7):491-6. PMID: 26270141
Purpose: To extract the Melaleuca sp. oil and to assess its in vitro inhibitory effect against Staphylococcus aureus isolates obtained from lower limb wounds and resistant to several antibiotics. Methods:...
10.
Falci S, Teixeira M, das Chagas P, Martinez B, Loyola A, Ferreira L, et al.
Acta Cir Bras . 2015 Jun; 30(6):401-6. PMID: 26108028
Purpose: To extract the Melaleuca sp. oil and to assess its in vitro inhibitory effect against Staphylococcus aureus isolates obtained from lower limb wounds and resistant to several antibiotics. Methods:...