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Pablo Cacabelos

Explore the profile of Pablo Cacabelos including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 99
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Recent Articles
1.
Cacabelos R, Carrera I, Martinez O, Alejo R, Fernandez-Novoa L, Cacabelos P, et al.
Med Res Rev . 2021 Jun; 41(5):2841-2886. PMID: 34106485
Atremorine is a novel bioproduct obtained by nondenaturing biotechnological processes from a genetic species of Vicia faba. Atremorine is a potent dopamine (DA) enhancer with powerful effects on the neuronal...
2.
Cacabelos R, Carril J, Corzo L, Fernandez-Novoa L, Pego R, Cacabelos N, et al.
Pharmaceuticals (Basel) . 2021 Apr; 14(4). PMID: 33920985
Background: Mood disorders represent a risk factor for dementia and are present in over 60% of cases with Alzheimer's disease (AD). More than 80% variability in drug pharmacokinetics and pharmacodynamics...
3.
Cacabelos R, Carrera I, Alejo R, Fernandez-Novoa L, Cacabelos P, Corzo L, et al.
Planta Med . 2019 Sep; 85(17):1351-1362. PMID: 31559607
Atremorine is a novel bioproduct with neuroprotective effects on dopaminergic neurons and a natural L-DOPA donor in Parkinson's disease (PD). In the present study, we show the effects of a...
4.
Cacabelos R, Carril J, Cacabelos N, Kazantsev A, Vostrov A, Corzo L, et al.
Int J Mol Sci . 2019 Mar; 20(5). PMID: 30871086
Sirtuins (SIRT1-7) are NAD⁺-dependent protein deacetylases/ADP ribosyltransferases with important roles in chromatin silencing, cell cycle regulation, cellular differentiation, cellular stress response, metabolism and aging. Sirtuins are components of the epigenetic...
5.
Cacabelos R, Meyyazhagan A, Carril J, Cacabelos P, Teijido O
J Pers Med . 2018 Jan; 8(1). PMID: 29301387
Alzheimer's disease (AD) is a polygenic/complex disorder in which genomic, epigenomic, cerebrovascular, metabolic, and environmental factors converge to define a progressive neurodegenerative phenotype. Pharmacogenetics is a major determinant of therapeutic...
6.
Cacabelos R, Torrellas C, Carrera I, Cacabelos P, Corzo L, Fernandez-Novoa L, et al.
CNS Neurol Disord Drug Targets . 2016 Feb; 15(2):141-241. PMID: 26831267
Dementia represents a major problem of health and disability, with a relevant economic impact on our society. Despite important advances in pathogenesis, diagnosis and treatment, its primary causes still remain...
7.
Cacabelos R, Cacabelos P, Torrellas C, Tellado I, Carril J
Methods Mol Biol . 2014 Aug; 1175:323-556. PMID: 25150875
Alzheimer's disease (AD) is a major problem of health and disability, with a relevant economic impact on our society. Despite important advances in pathogenesis, diagnosis, and treatment, its primary causes...