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P Zelazowski

Explore the profile of P Zelazowski including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 25
Citations 317
Followers 0
Related Specialties
Allergy & Immunology
Neurology
Endocrinology
Top 10 Co-Authors
C M Snapper
M Pawlikowski
H Stepien
T GOSCICKA
K Szewczyk
M R Kehry
F R Rosas
Y Shen
H Dlugonska
W Rudnicka
Published In
J Immunol
Neuroendocrinology
Bull Acad Pol Sci Biol
Int Immunol
Trends Immunol
Affiliations
Soon will be listed here.
Recent Articles
1.
Distinct types of T-cell help for the induction of a humoral immune response to Streptococcus pneumoniae
Snapper C, Shen Y, Khan A, Colino J, Zelazowski P, Mond J, et al.
Trends Immunol . 2001 May; 22(6):308-11. PMID: 11377289
Studies have indicated that purified soluble polysaccharide antigens can elicit T cell-independent Ig responses in vivo, although these responses can be modulated by T cells in a noncognate manner. Relatively...
2.
NF-kappaB/p50 and NF-kappaB/c-Rel differentially regulate the activity of the 3'alphaE-hsl,2 enhancer in normal murine B cells in an activation-dependent manner
Zelazowski P, Shen Y, Snapper C
Int Immunol . 2000 Aug; 12(8):1167-72. PMID: 10917891
The enhancer complex located 3' to the C(H)alpha gene in the IgH locus (3alphaE) may regulate B cell function through its ability to act as a locus control region. Multiple,...
3.
The p65 subunit of NF-kappa B is redundant with p50 during B cell proliferative responses, and is required for germline CH transcription and class switching to IgG3
Horwitz B, Zelazowski P, Shen Y, Wolcott K, Scott M, Baltimore D, et al.
J Immunol . 1999 Feb; 162(4):1941-6. PMID: 9973462
B cells lacking individual NF-kappa B/Rel family members exhibit defects in activation programs. We generated small resting B cells lacking p65 or p50 alone, or lacking both p50 and p65,...
4.
B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching
Zelazowski P, Carrasco D, Rosas F, Moorman M, Bravo R, Snapper C
J Immunol . 1997 Oct; 159(7):3133-9. PMID: 9317110
The Ig heavy chain locus contains a number of binding sites for the transcriptional activator, c-Rel. In this study, we evaluated the capacity of B cells from mice made genetically...
5.
Regulation of Ku expression in normal murine B cells by stimuli that promote switch recombination
Zelazowski P, Max E, Kehry M, Snapper C
J Immunol . 1997 Sep; 159(6):2559-62. PMID: 9300672
DNA-dependent protein kinase, the catalytic subunit associated with the Ku heterodimer (Ku70/Ku86), has been implicated in switch recombination. Therefore, we tested whether certain stimuli known to promote switch recombination may...
6.
The immunoglobulin class switch: beyond "accessibility"
Snapper C, Marcu K, Zelazowski P
Immunity . 1997 Mar; 6(3):217-23. PMID: 9075922
No abstract available.
7.
B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching
Snapper C, Rosas F, Zelazowski P, Moorman M, Kehry M, Bravo R, et al.
J Exp Med . 1996 Oct; 184(4):1537-41. PMID: 8879226
A number of distinct functional abnormalities have been observed in B cells derived from p50/ NF-kappa B or c-rel knockout mice. RelB, another member of the NF-kappa B/Rel family of...
8.
IL-10 selectively regulates murine Ig isotype switching
Shparago N, Zelazowski P, Jin L, McIntyre T, Stuber E, Pecanha L, et al.
Int Immunol . 1996 May; 8(5):781-90. PMID: 8671667
A role for IL-10 in regulating Ig isotype switching directly at the level of the murine B cell has not been previously reported. In this report we show that IL-10...
9.
B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching
Snapper C, Zelazowski P, Rosas F, Kehry M, Tian M, Baltimore D, et al.
J Immunol . 1996 Jan; 156(1):183-91. PMID: 8598461
To better understand the role of NF-kappaB in normal B cell physiology, we used a purified population of resting B cells from p50/NF-kappa B knockout (p50-/-) mice to determine their...
10.
Antigen receptor cross-linking differentially regulates germ-line CH ribonucleic acid expression in murine B cells
Zelazowski P, Collins J, Dunnick W, Snapper C
J Immunol . 1995 Feb; 154(3):1223-31. PMID: 7529796
Cytokines are believed to regulate Ig class switching, in part, through selective modulation of germ-line constant heavy (CH) gene transcription. B cell activators such as LPS or activated T cell...