P van Sluis
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Explore the profile of P van Sluis including associated specialties, affiliations and a list of published articles.
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15
Citations
755
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Recent Articles
1.
Das S, Bryan K, Buckley P, Piskareva O, Bray I, Foley N, et al.
Oncogene
. 2012 Jul;
32(24):2927-36.
PMID: 22797059
MicroRNAs (miRNAs) contribute to the pathogenesis of many forms of cancer, including the pediatric cancer neuroblastoma, but the underlying mechanisms leading to altered miRNA expression are often unknown. Here, a...
2.
Santo E, Ebus M, Koster J, Schulte J, Lakeman A, van Sluis P, et al.
Oncogene
. 2011 Aug;
31(12):1571-81.
PMID: 21860421
Neuroblastoma tumors frequently show loss of heterozygosity of chromosome 11q with a shortest region of overlap in the 11q23 region. These deletions are thought to cause inactivation of tumor suppressor...
3.
Spieker N, Beitsma M, van Sluis P, Chan A, Caron H, Versteeg R
Genes Chromosomes Cancer
. 2001 Apr;
31(2):172-81.
PMID: 11319804
Deletions in the short arm of chromosome 1 (1p36) and MYCN amplification are common in neuroblastoma. Previously we showed evidence of at least two different neuroblastoma tumor-suppressor loci on 1p....
4.
Boon K, Caron H, van Asperen R, Valentijn L, Hermus M, van Sluis P, et al.
EMBO J
. 2001 Mar;
20(6):1383-93.
PMID: 11250904
The myc oncogenes are frequently activated in human tumors, but there is no comprehensive insight into the target genes and downstream cellular pathways of these transcription factors. We applied serial...
5.
Caron H, van Schaik B, van der Mee M, Baas F, Riggins G, van Sluis P, et al.
Science
. 2001 Feb;
291(5507):1289-92.
PMID: 11181992
The chromosomal position of human genes is rapidly being established. We integrated these mapping data with genome-wide messenger RNA expression profiles as provided by SAGE (serial analysis of gene expression)....
6.
Spieker N, van Sluis P, Beitsma M, Boon K, van Schaik B, van Kampen A, et al.
Genomics
. 2001 Feb;
71(2):214-21.
PMID: 11161815
Neuroblastoma is an embryonal tumor originating from neural crest-derived cells. Here we present the serendipitous cloning of amplified sequences of chromosome 2p15 in neuroblastoma cell line IMR32. The amplified region...
7.
Caron H, Spieker N, Godfried M, Veenstra M, van Sluis P, de Kraker J, et al.
Genes Chromosomes Cancer
. 2001 Jan;
30(2):168-74.
PMID: 11135433
A previous loss of heterozygosity (LOH) study of a series of 91 neuroblastomas suggested that the 1p35-36 region encodes at least two tumor suppressor genes (TSGs) of importance in neuroblastoma...
8.
Spieker N, Beitsma M, van Sluis P, Roobeek I, den Dunnen J, Speleman F, et al.
Genes Chromosomes Cancer
. 1999 Dec;
27(2):143-52.
PMID: 10612802
Common genetic aberrations of neuroblastoma are deletions of the short arm of chromosome 1 (1p36) and MYCN amplification. Our deletion analysis of 25 tumor cell lines and 171 tumors strongly...
9.
Caron H, van Sluis P, Buschman R, Pereira do Tanque R, Maes P, Beks L, et al.
Hum Genet
. 1996 Jun;
97(6):834-7.
PMID: 8641706
Neuroblastoma is a childhood neural crest tumour, genetically characterized by frequent deletions of the short arm of chromosome 1 and amplification of N-myc. Here we report the first evidence for...
10.
Caron H, van Sluis P, de Kraker J, Bokkerink J, Egeler M, Laureys G, et al.
N Engl J Med
. 1996 Jan;
334(4):225-30.
PMID: 8531999
Background: Neuroblastoma is a childhood tumor derived from cells of the neural crest, with a widely variable outcome. Differences in the behavior and prognosis of the tumor suggest that neuroblastoma...