P Trayhurn
Overview
Explore the profile of P Trayhurn including associated specialties, affiliations and a list of published articles.
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Articles
197
Citations
3457
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Recent Articles
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2.
Gentili A, Zaibi M, Alomar S, De Vuono S, Ricci M, Alaeddin A, et al.
Horm Metab Res
. 2016 Jun;
48(12):847-853.
PMID: 27300476
The aim of the study was to investigate the involvement of the adipokines eotaxin-3, MIP-1β, and MCP-4 in obesity and related comorbidities and the modification of their circulating levels after...
3.
Muller M, Baracos V, Bosy-Westphal A, Dulloo A, Eckel J, Fearon K, et al.
Obes Rev
. 2014 May;
15(8):640-56.
PMID: 24835453
The 12th Stock Conference addressed body composition and related functions in two extreme situations, obesity and cancer cachexia. The concept of 'functional body composition' integrates body components into regulatory systems...
4.
Mejhert N, Wilfling F, Esteve D, Galitzky J, Pellegrinelli V, Kolditz C, et al.
Diabetologia
. 2013 May;
56(8):1792-801.
PMID: 23666167
Aims/hypothesis: Alterations in white adipose tissue (WAT) function, including changes in protein (adipokine) secretion and extracellular matrix (ECM) composition, promote an insulin-resistant state. We set out to identify novel adipokines...
5.
Gao D, Trayhurn P, Bing C
Int J Obes (Lond)
. 2012 Apr;
37(3):357-65.
PMID: 22508334
Background: Adipose tissue expansion during obesity is associated with a state of low-grade inflammation and an increase in macrophage infiltration, which predisposes to insulin resistance and vascular malfunction. Growing evidence...
6.
Ryan V, Trayhurn P, Hunter L, Morris P, German A
Domest Anim Endocrinol
. 2011 Jul;
41(3):150-61.
PMID: 21798686
The enzyme 11β-hydroxysteroid dehydrogenase 1 (11β-HSD-1) is expressed in a number of tissues in rodents and humans and is responsible for the reactivation of inert cortisone into cortisol. Its gene...
7.
Packer M, German A, Hunter L, Trayhurn P, Proudman C
Equine Vet J Suppl
. 2011 Jul;
(39):26-33.
PMID: 21790751
Reasons For Performing Study: Adipose tissue is an important source of inflammatory cytokines (adipokines) and adiposity has been identified as having a significant effect on human morbidity and mortality. Obesity...
8.
Mracek T, Stephens N, Gao D, Bao Y, Ross J, Ryden M, et al.
Br J Cancer
. 2011 Jan;
104(3):441-7.
PMID: 21245862
Background: Profound loss of adipose tissue is a hallmark of cancer cachexia. Zinc-α2-glycoprotein (ZAG), a recently identified adipokine, is suggested as a candidate in lipid catabolism. Methods: In the first...
9.
Gonzalez-Muniesa P, Bing C, Trayhurn P
Horm Metab Res
. 2010 Jul;
42(10):710-7.
PMID: 20603779
Inflammation in adipose tissue is a characteristic of obesity and the metabolic syndrome. It is suggested that the endocannabinoid system is involved in the regulation of inflammatory and angiogenic processes...
10.
Gao D, Trayhurn P, Bing C
Mol Cell Endocrinol
. 2010 Jul;
325(1-2):135-42.
PMID: 20595026
Zinc-alpha2-glycoprotein (ZAG), a novel adipokine, is downregulated in adipose tissue in obesity, a state characterized by increased adipose tissue macrophage infiltration and chronic low-grade inflammation. This study investigated whether macrophage-secreted...