P Toby H Coates
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Explore the profile of P Toby H Coates including associated specialties, affiliations and a list of published articles.
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40
Citations
718
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Recent Articles
1.
Chung W, Pollard C, Kumar R, Drogemuller C, Naziruddin B, Stover C, et al.
Ann Transl Med
. 2021 Feb;
9(2):98.
PMID: 33569400
Background: The initial response to islet transplantation and the subsequent acute inflammation is responsible for significant attrition of islets following both autologous and allogenic procedures. This multicentre study compares this...
2.
Burzava A, Forget A, Harding F, Cockshell M, Penko D, Rouzaud C, et al.
Biointerphases
. 2019 Feb;
14(1):011002.
PMID: 30700091
PolyJet three-dimensional (3D) printing allows for the rapid manufacturing of 3D moulds for the fabrication of cross-linked poly(dimethylsiloxane) microwell arrays (PMAs). As this 3D printing technique has a resolution on...
3.
Li J, Yong T, Rao M, Coates P
NDT Plus
. 2015 May;
2(4):312-3.
PMID: 25984025
The increased risk of malignancies is a well-recognized complication of organ transplantation. When renal cell carcinoma (RCC) occurs in kidney transplant recipients, less than 10% of it affects the allograft....
4.
Fuss A, Hope C, Deayton S, Bennett G, Holdsworth R, Carroll R, et al.
Nephrology (Carlton)
. 2015 Mar;
20(7):467-73.
PMID: 25726938
Aims: Acute antibody-mediated rejection can occur in absence of circulating donor-specific antibodies. Agonistic antibodies targeting the anti-angiotensin II type 1 receptor (anti-AT1 R) are emerging as important non-human leucocyte antigen...
5.
Pathiraja V, Kuehlich J, Campbell P, Krishnamurthy B, Loudovaris T, Coates P, et al.
Diabetes
. 2014 Aug;
64(1):172-82.
PMID: 25157096
Type 1 diabetes (T1D) develops when insulin-secreting β-cells, found in the pancreatic islets of Langerhans, are destroyed by infiltrating T cells. How human T cells recognize β-cell-derived antigens remains unclear....
6.
Hanf W, Bonder C, Coates P
J Immunol Res
. 2014 Apr;
2014:549315.
PMID: 24741606
Transplant glomerulopathy (TG) is a major cause of chronic graft dysfunction without effective therapy. Although the histological definition of TG is well characterized, the pathophysiological pathways leading to TG development...
7.
Peiris H, Bonder C, Coates P, Keating D, Jessup C
Diabetes
. 2013 Dec;
63(1):3-11.
PMID: 24357688
Within the pancreatic islet, the β-cell represents the ultimate biosensor. Its central function is to accurately sense glucose levels in the blood and consequently release appropriate amounts of insulin. As...
8.
Penko D, Rojas-Canales D, Mohanasundaram D, Peiris H, Sun W, Drogemuller C, et al.
Cell Transplant
. 2013 Sep;
24(1):37-48.
PMID: 24069942
The success of pancreatic islet transplantation is limited by delayed engraftment and suboptimal function in the longer term. Endothelial progenitor cells (EPCs) represent a potential cellular therapy that may improve...
9.
Hughes A, Mohanasundaram D, Kireta S, Jessup C, Drogemuller C, Coates P
Transplantation
. 2013 Feb;
95(5):671-8.
PMID: 23364485
Background: The early loss of functional islet mass (50-70%) due to apoptosis after clinical transplantation contributes to islet allograft failure. Insulin-like growth factor (IGF)-II is an antiapoptotic protein that is...
10.
Itoh T, Iwahashi S, Kanak M, Shimoda M, Takita M, Chujo D, et al.
Cell Transplant
. 2012 Dec;
23(2):153-65.
PMID: 23211332
A major problem after clinical autologous islet transplantation (AIT) is the difficulty in achieving insulin independence. To follow up on our demonstration in a murine model that high-mobility group box...