P Sipkema
Overview
Explore the profile of P Sipkema including associated specialties, affiliations and a list of published articles.
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Articles
88
Citations
808
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Recent Articles
1.
van Nieuw Amerongen G, Musters R, Eringa E, Sipkema P, van Hinsbergh V
Am J Physiol Cell Physiol
. 2008 Mar;
294(5):C1234-41.
PMID: 18353893
Endothelial hyperpermeability is regulated by a myosin light chain-2 (MLC2) phosphorylation-dependent contractile mechanism. Thrombin is a potent inducer of hyperpermeability of cultured monolayers of endothelial cells (ECs) via Rho kinase-mediated...
2.
Versteilen A, Di Maggio F, Leemreis J, Groeneveld A, Musters R, Sipkema P
Int J Artif Organs
. 2005 Jan;
27(12):1019-29.
PMID: 15645611
Acute renal failure (ARF) necessitating renal replacement therapy is a common problem associated with high morbidity and mortality in the critically ill. Hypotension, followed by resuscitation, is the most common...
3.
Smolders R, van der Mooren M, Sipkema P, Kenemans P
Gynecol Endocrinol
. 2003 Sep;
17(4):339-54.
PMID: 14503980
Estrogens influence the independent cardiovascular risk factor homocysteine as well as vasodilatation. Homocysteine alone also influences vasodilatation, indicating a relational triangle that seems important in interpreting the isolated effects of...
4.
Bakker E, Versluis J, Sipkema P, Vanteeffelen J, Rolf T, Spaan J, et al.
J Physiol
. 2003 Mar;
548(Pt 2):549-55.
PMID: 12611919
We tested the hypothesis that under physiological conditions, arterioles match their diameter to the level of shear stress. Haemodynamic and anatomical data were obtained in segments of the first-order arteriole...
5.
Lamberts R, van Rijen M, Sipkema P, Fransen P, Sys S, Westerhof N
Am J Physiol Heart Circ Physiol
. 2002 Mar;
282(4):H1334-40.
PMID: 11893569
The role of stretch-activated ion channels (SACs) in coronary perfusion-induced increase in cardiac contractility was investigated in isolated isometrically contracting perfused papillary muscles from Wistar rats. A brief increase in...
6.
Piepot H, Groeneveld A, van Lambalgen A, Sipkema P
Clin Sci (Lond)
. 2002 Mar;
102(3):297-305.
PMID: 11869170
We investigated whether organ-specific differences exist in the role of inducible nitric oxide synthase (iNOS) in hyporeactivity to vasoconstrictors following 20 h in vitro exposure of isolated superior mesenteric, renal,...
7.
Versluis J, Heslinga J, Sipkema P, Westerhof N
Am J Physiol Heart Circ Physiol
. 2001 Oct;
281(5):H1913-8.
PMID: 11668051
Pressure-flow relationships at the entrance of the coronary circulation in the diastolic myocardium exhibit a zero-flow pressure intercept (P(int)). We tested whether this intercept is the same throughout the vascular...
8.
Willemsen M, Duncker D, Krams R, Dijkman M, Lamberts R, Sipkema P, et al.
Am J Physiol Heart Circ Physiol
. 2001 Jul;
281(2):H731-7.
PMID: 11454577
Coronary arterial inflow is impeded and venous outflow is increased as a result of the decrease in coronary vascular volume due to cardiac contraction. We evaluated whether cardiac contraction is...
9.
Groeneveld A, Sipkema P
Crit Care Med
. 2000 Jul;
28(6):2161-2.
PMID: 10890696
No abstract available.
10.
Piepot H, Boer C, Groeneveld A, van Lambalgen A, Sipkema P
Kidney Int
. 2000 Jun;
57(6):2502-10.
PMID: 10844619
Background: Impaired endothelium-dependent vasodilation may contribute to hypoperfusion and failure of abdominal organs, including the kidneys during endotoxin or septic shock. In this study, the short-term (2 h) effects of...