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P Shabram

Explore the profile of P Shabram including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 136
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Recent Articles
1.
Ramachandra M, Rahman A, Zou A, Vaillancourt M, Howe J, Antelman D, et al.
Nat Biotechnol . 2001 Nov; 19(11):1035-41. PMID: 11689848
Replicating adenoviruses may prove to be effective anticancer agents if they can be engineered to selectively destroy tumor cells. We have constructed a virus (01/PEME) containing a novel regulatory circuit...
2.
Rahman A, Tsai V, Goudreau A, Shinoda J, Wen S, Ramachandra M, et al.
Mol Ther . 2001 May; 3(5 Pt 1):768-78. PMID: 11356081
Recombinant adenoviral (rAd) vectors are capable of mediating high-efficiency gene transfer in vivo. Under conditions requiring systemic administration, however, the use of rAd vectors can be problematic due to the...
3.
Shabram P, Aguilar-Cordova E
Mol Ther . 2000 Nov; 2(5):420-1. PMID: 11082315
No abstract available.
4.
Atencio I, Ramachandra M, Shabram P, Demers G
Cell Growth Differ . 2000 Jun; 11(5):247-53. PMID: 10845425
Reports suggest a role of calpains in degradation of wild-type p53, which may regulate p53 induction of apoptosis. A calpain inhibitor, n-acetyl-leu-leu-norleucinal (calpain inhibitor 1), was assessed for ability to...
5.
Shabram P, Li W, Giroux D, Aguilar-Cordova E
Nat Med . 1997 Jul; 3(7):808-11. PMID: 9212113
No abstract available.
6.
Huyghe B, Liu X, Sutjipto S, Sugarman B, Horn M, Shepard H, et al.
Hum Gene Ther . 1995 Nov; 6(11):1403-16. PMID: 8573613
We have investigated the use of column chromatography for the purification of ACN53, a recombinant adenovirus type 5 encoding the human p53 tumor suppressor protein. Anion exchange, size exclusion, hydrophobic...