P S Parfrey
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Explore the profile of P S Parfrey including associated specialties, affiliations and a list of published articles.
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Articles
171
Citations
4807
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Recent Articles
1.
Parfrey P, Dicks E, Parfrey O, McNicholas P, Noseworthy H, Woods M, et al.
Clin Genet
. 2016 Oct;
91(5):672-682.
PMID: 27696385
As Newfoundland has the highest rate of familial colorectal cancer (CRC) in the world, we started a population-based clinic to provide colonoscopic and Lynch syndrome (LS) screening recommendations to families...
2.
Chang T, Abdalla S, London G, Block G, Correa-Rotter R, Drueke T, et al.
J Hum Hypertens
. 2015 Jun;
30(3):204-9.
PMID: 26040438
Patients with end-stage renal disease often have derangements in calcium and phosphorus homeostasis and resultant secondary hyperparathyroidism (sHPT), which may contribute to the high prevalence of arterial stiffness and hypertension....
3.
Zhu Y, Yang S, Wang P, Savas S, Wish T, Green R, et al.
Br J Cancer
. 2014 Jan;
110(5):1359-66.
PMID: 24448365
Background: Smoking is a risk factor for incident colorectal cancer (CRC); however, it is unclear about its influence on survival after CRC diagnosis. Methods: A cohort of 706 CRC patients...
4.
Stuckless S, Green J, Dawson L, Barrett B, Woods M, Dicks E, et al.
Clin Genet
. 2012 Jul;
83(4):359-64.
PMID: 22775459
Lifetime risk of developing endometrial cancer in Lynch syndrome carriers is very high and females are also at an increased risk of developing ovarian cancer. The aim of the study...
5.
Hodgkinson K, Connors S, Merner N, Haywood A, Young T, McKenna W, et al.
Clin Genet
. 2012 Jun;
83(4):321-31.
PMID: 22725725
To determine the phenotype and natural history of a founder genetic subtype of autosomal dominant arrhythmogenic right ventricular cardiomyopathy (ARVC) caused by a p.S358L mutation in TMEM43. The age of...
6.
Stuckless S, Green J, Morgenstern M, Kennedy C, Green R, Woods M, et al.
Clin Genet
. 2011 Oct;
82(5):439-45.
PMID: 22011075
The lifetime risk of developing colorectal cancer (CRC) in Lynch syndrome (LS) carriers is very high. To determine the impact of colonoscopic screening in 54 male and 98 female MSH2...
7.
Rawson J, Mrkonjic M, Daftary D, Dicks E, Buchanan D, Younghusband H, et al.
Br J Cancer
. 2011 May;
104(12):1906-12.
PMID: 21587258
Background: In colorectal cancer (CRC), tumour microsatellite instability (MSI) status and CpG island methylator phenotype (CIMP) status are indicators of patient outcome, but the molecular events that give rise to...
8.
Woods M, Younghusband H, Parfrey P, Gallinger S, McLaughlin J, Dicks E, et al.
Gut
. 2010 Aug;
59(10):1369-77.
PMID: 20682701
Background And Aims: Colorectal cancer (CRC) is the second most frequent cancer in developed countries. Newfoundland has the highest incidence of CRC in Canada and the highest rate of familial...
9.
Moore S, Buckley D, Macmillan A, Marshall H, Steele L, Ray P, et al.
Clin Genet
. 2008 Aug;
74(3):213-22.
PMID: 18684116
The neuronal ceroid lipofuscinoses (NCLs) are the commonest neurodegenerative disorders of children. The aims of this study were to determine the incidence of NCL in Newfoundland, identify the causative genes,...
10.
Green R, Green J, Buehler S, Robb J, Daftary D, Gallinger S, et al.
Fam Cancer
. 2006 Oct;
6(1):53-62.
PMID: 17039269
Newfoundland has the highest rate of colorectal cancer (CRC) of any Canadian province. In order to investigate the factors, especially genetic components, responsible for CRC we established the Newfoundland Colorectal...