P R Hoban
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Explore the profile of P R Hoban including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
381
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Recent Articles
1.
Mamutse G, Woolmore J, Pye E, Partridge J, Boggild M, Young C, et al.
Mult Scler
. 2008 Jul;
14(9):1280-3.
PMID: 18653739
Ultraviolet radiation (UVR) may contribute to multiple sclerosis (MS) outcome by a mechanism involving vitamin D and the vitamin D receptor (VDR). In 512 patients with MS duration of 10...
2.
Madan V, Hoban P, Strange R, Fryer A, Lear J
Br J Dermatol
. 2006 Jun;
155(1):217-8.
PMID: 16792784
No abstract available.
3.
Watts K, Cottrell E, Hoban P, Spiteri M
Respir Res
. 2006 Jun;
7:88.
PMID: 16776827
Background: Idiopathic Pulmonary Fibrosis (IPF) is a debilitating disease characterized by exaggerated extracellular matrix deposition and aggressive lung structural remodeling. Disease pathogenesis is driven by fibroblastic foci formation, consequent on...
4.
Smith S, Bowers N, Betticher D, Gautschi O, Ratschiller D, Hoban P, et al.
Br J Cancer
. 2005 Oct;
93(6):719-29.
PMID: 16222316
Aurora kinases are key regulators of chromosome segregation during mitosis. We have previously shown by microarray analysis of primary lung carcinomas and matched normal tissue that AURKB (22 out of...
5.
Strange R, El-Genidy N, Ramachandran S, Lovatt T, Fryer A, Smith A, et al.
Ann Hum Genet
. 2004 Dec;
68(Pt 6):536-45.
PMID: 15598212
Loss of function of the human patched gene (PTCH) is common and critical in basal cell carcinoma (BCC) development. Indirect evidence suggests polymorphism in PTCH mediates BCC risk. We studied...
6.
Howells R, Dhar K, Hoban P, Jones P, Fryer A, Redman C, et al.
Int J Gynecol Cancer
. 2004 Apr;
14(2):242-50.
PMID: 15086723
Ovarian cancer accounts for the majority of deaths from gynaecological malignancy, and polymorphisms in genes encoding the glutathione-S-transferase (GST) GSTP1 detoxifying enzymes may lead to variation in detoxification of carcinogens....
7.
Bruce C, Howard P, Nowak N, Hoban P
Cancer Genet Cytogenet
. 2003 Feb;
141(2):106-13.
PMID: 12606127
We have previously described the physical localization of a constitutional t(5;6)(q21;q21) in a patient (tumor cell sample designated as MA214) with bilateral Wilms tumor (WT). We have now physically refined...
8.
Holley S, Parkes G, Matthias C, Bockmuhl U, Jahnke V, Leder K, et al.
Am J Pathol
. 2001 Nov;
159(5):1917-24.
PMID: 11696452
We have previously reported that the cyclin D1 (CCND1) GG870 genotype was associated with poorly differentiated tumors and reduced disease-free interval in patients with squamous cell carcinoma of the head...
9.
Holland T, Elder J, McCloud J, Hall C, Deakin M, Fryer A, et al.
Int J Cancer
. 2001 Aug;
95(5):302-6.
PMID: 11494229
We investigated the expression of the cell cycle regulatory proteins cyclin D1 and p21(WAF1/CIP1) (p21) in human colorectal carcinomas using immunohistochemistry. Cyclin D1 was not detected in normal colonic epithelium;...
10.
Howells R, Holland T, Dhar K, Redman C, Hand P, Hoban P, et al.
Int J Gynecol Cancer
. 2001 May;
11(2):107-12.
PMID: 11328408
The objective of this study was to determine whether the association between GSTM1 null/GSTTI null and survival in ovarian cancer is mediated by the influence of these genes on p53...