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P N Barlow

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Articles 38
Citations 980
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Recent Articles
1.
Schmidt C, Herbert A, Hocking H, Uhrin D, Barlow P
Clin Exp Immunol . 2007 Dec; 151(1):14-24. PMID: 18081691
The 155-kDa glycoprotein, complement factor H (CFH), is a regulator of complement activation that is abundant in human plasma. Three-dimensional structures of over half the 20 complement control protein (CCP)...
2.
Herbert A, OLeary J, Atkinson J, Barlow P
Biochem Soc Trans . 2002 Nov; 30(Pt 6):990-6. PMID: 12440959
Members of the regulator of complement activation (RCA) protein family perform a vital role in health and disease. In this report we describe our efforts to solve the structures of...
3.
Kirkitadze M, Barlow P
Immunol Rev . 2001 Jun; 180:146-61. PMID: 11414356
In this review we summarise more than 10 years of biophysical exploration into the structural biology of the regulators of complement activation (RCA). The five human proteins responsible for regulation...
4.
Bramham J, Smith B, Uhrin D, Barlow P, Winder S
J Biomol NMR . 2001 Mar; 19(2):189-90. PMID: 11256815
No abstract available.
5.
Henderson C, Bromek K, Mullin N, Smith B, Uhrin D, Barlow P
J Mol Biol . 2001 Mar; 307(1):323-39. PMID: 11243823
The complement control protein (CCP) module (also known as SCR, CCP or sushi domain) is prevalent amongst proteins that regulate complement activation. Functional and mutagenesis studies have shown that in...
6.
Uhrinova S, Uhrin D, Nairn J, Price N, Fothergill-Gilmore L, Barlow P
J Mol Biol . 2001 Mar; 306(2):275-90. PMID: 11237600
The structure and backbone dynamics of a double labelled (15N,13C) monomeric, 23.7 kD phosphoglycerate mutase (PGAM) from Schizosaccharomyces pombe have been investigated in solution using NMR spectroscopy. A set of...
7.
Murthy K, Smith S, Ganesh V, Judge K, Mullin N, Barlow P, et al.
Cell . 2001 Feb; 104(2):301-11. PMID: 11207370
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of request of the editors. Cell is retracting this...
8.
Uhrin D, Bramham J, Winder S, Barlow P
J Biomol NMR . 2001 Jan; 18(3):253-9. PMID: 11142515
Based on the HSQC scheme, we have designed a 2D heterocorrelated experiment which combines constant time (CT) 13C and variable time (VT) 15N chemical shift labelling. Although applicable to all...
9.
Nairn J, Duncan D, Price N, Kelly S, Fothergill-Gilmore L, Uhrinova S, et al.
Eur J Biochem . 2000 Dec; 267(24):7065-74. PMID: 11106417
The roles of a number of amino acids present at the active site of the monomeric phosphoglycerate mutase from the fission yeast Schizosaccharomyces pombe have been explored by site-directed mutagenesis....
10.
Free A, Wakefield R, Smith B, Dryden D, Barlow P, Bird A
J Biol Chem . 2000 Oct; 276(5):3353-60. PMID: 11035019
The methyl-CpG binding domain (MBD) of the transcriptional repressor MeCP2 has been proposed to recognize a single symmetrically methylated CpG base pair via hydrophobic patches on an otherwise positively charged...