P Mark Hogarth
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Explore the profile of P Mark Hogarth including associated specialties, affiliations and a list of published articles.
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112
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2501
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Recent Articles
1.
Hsin L, Hew M, Aui P, Deckert K, Hogarth P, OHehir R, et al.
Allergy
. 2025 Mar;
PMID: 40052465
Background: Allergic rhinitis and asthma can be triggered by a variety of aeroallergens, including house dust mites (HDM), tree and grass pollen, and household pets. Identification of the relevant allergen...
2.
Quang C, Anderson J, Russell F, Reyburn R, Ratu T, Tuivaga E, et al.
Nat Commun
. 2025 Mar;
16(1):2130.
PMID: 40032823
The WHO has given a permissive recommendation for an off-label one-dose human papillomavirus (HPV) vaccine schedule to prevent cervical cancer, based on evidence of comparable protection to two or three...
3.
Aurelia L, Purcell R, Theisen R, Kelly A, Esterbauer R, Ramanathan P, et al.
Sci Adv
. 2025 Feb;
11(9):eads1482.
PMID: 40009690
Repeated mRNA COVID-19 vaccination increases spike-specific immunoglobulin G4 (IgG4) titers. Here, we characterized the influence of increased IgG4 titers on a range of Fc-mediated responses. Elevated spike-specific IgG4 reduced binding...
4.
Harris A, Kurtovic L, Nogueira J, Bouzas I, Opi D, Wines B, et al.
Commun Med (Lond)
. 2024 Dec;
4(1):273.
PMID: 39702507
Background: SARS-CoV-2 transmission and COVID-19 disease severity is influenced by immunity from natural infection and/or vaccination. Population-level immunity is complicated by the emergence of viral variants. Antibody Fc-dependent effector functions...
5.
Grobben M, Bakker M, Schriek A, Levels L, Umotoy J, Tejjani K, et al.
PLoS Pathog
. 2024 Dec;
20(12):e1012739.
PMID: 39661636
HIV-1 infection leads to chronic disease requiring life-long treatment and therefore alternative therapeutics, a cure and/or a protective vaccine are needed. Antibody-mediated effector functions could have a role in the...
6.
Oxley E, Kershaw N, Louis C, Goodall K, Garwood M, Jee Ho S, et al.
Cell Rep
. 2024 Oct;
43(10):114834.
PMID: 39383033
T cell surface CTLA4 sequesters the costimulatory ligands CD80 and CD86 on antigen-presenting cells (APCs) to prevent autoimmunity. Therapeutic immunosuppression by recombinant CTLA4-immunoglobulin (Ig) fusion proteins, including abatacept, is also...
7.
Whitehead C, Wines B, Davies A, McDonnell J, Trist H, Esparon S, et al.
Immunol Rev
. 2024 Oct;
328(1):438-455.
PMID: 39364646
Advances in antibody engineering are being directed at the development of next generation immunotherapeutics with improved potency. Hexamerisation of IgG is a normal physiological aspect of IgG biology and recently...
8.
von Borstel A, Reinwald S, Aui P, McKenzie C, Varese N, Hogarth P, et al.
Allergy
. 2024 Sep;
80(3):867-869.
PMID: 39268605
No abstract available.
9.
McKenzie C, Reinwald S, Averso B, Spurrier B, Satz A, von Borstel A, et al.
J Allergy Clin Immunol
. 2024 Sep;
154(6):1511-1522.
PMID: 39218358
Background: Allergen immunotherapy (AIT) is the only disease-modifying treatment for allergic disorders. We have recently discovered that allergen-specific memory B cells (Bmem) are phenotypically altered after 4 months of sublingual...
10.
Fryer H, Geers D, Gommers L, Zaeck L, Tan N, Jones-Freeman B, et al.
J Infect
. 2024 Aug;
89(4):106246.
PMID: 39127451
Bivalent COVID-19 vaccines comprising ancestral Wuhan-Hu-1 (WH1) and the Omicron BA.1 or BA.5 subvariant elicit enhanced serum antibody responses to emerging Omicron subvariants. Here, we characterized the RBD-specific memory B...