P M Hogarth
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Explore the profile of P M Hogarth including associated specialties, affiliations and a list of published articles.
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104
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1146
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Recent Articles
1.
Wines B, Tan C, Duncan E, McRae S, Baker R, Andrews R, et al.
J Thromb Haemost
. 2018 Oct;
16(12):2520-2525.
PMID: 30269432
Essentials FcγRIIa mediates life-threatening heparin-induced thrombocytopenia (HIT). Most anti-platelet factor (PF)4-heparin IgGs are not pathogenic so diagnosis of HIT is challenging. Dimeric rsFcγRIIa was used to quantify receptor-binding activity of...
2.
Barnes N, Powell M, Trist H, Gavin A, Wines B, Hogarth P
Immunol Lett
. 2005 Dec;
104(1-2):118-23.
PMID: 16375976
Ligand-dependent aggregation of FcgammaRIIa initiates multiple biochemical processes including the translocation to detergent resistant membrane domains (DRMs) and receptor tyrosine phosphorylation. Palmitoylation of cysteine residues is considered to be one...
3.
Hulett M, Pagler E, Hornby J, Hogarth P, Eyre H, Baker E, et al.
Biochem Biophys Res Commun
. 2001 Feb;
280(1):374-9.
PMID: 11162526
CD20 and the beta subunit of the high affinity receptor for IgE (FcepsilonRIbeta) are related four-transmembrane molecules that are expressed on the surface of hematopoietic cells and play crucial roles...
4.
Wines B, Sardjono C, Trist H, Lay C, Hogarth P
J Immunol
. 2001 Feb;
166(3):1781-9.
PMID: 11160224
This study defines the molecular basis of the FcalphaRI (CD89):IgA interaction, which is distinct from that of the other leukocyte Fc receptors and their Ig ligands. A comprehensive analysis using...
5.
Gavin A, Leiter E, Hogarth P
Immunogenetics
. 2001 Feb;
51(3):206-11.
PMID: 10752630
The mouse Fcgr1 gene encoding the high-affinity IgG receptor (FcgammaRI) exists as two known alleles, FcgammaRI-BALB and FcgammaRI-NOD, and these alleles exhibit functional differences. To determine whether other alleles exist...
6.
Trist H, Snider J, Hulett M, Hogarth P, Rigby L, Epa V
Allergy
. 2000 Aug;
55(7):609-19.
PMID: 10921459
Defining the structure of the human high-affinity receptor for IgE, Fc,RI, is crucial to understand the receptor:ligand interaction, and to develop drugs to prevent IgE-dependent allergic diseases. To this end,...
7.
Wines B, Powell M, Parren P, Barnes N, Hogarth P
J Immunol
. 2000 May;
164(10):5313-8.
PMID: 10799893
The CH2-CH3 interface of the IgG Fc domain contains the binding sites for a number of Fc receptors including Staphylococcal protein A and the neonatal Fc receptor (FcRn). It has...
8.
Vukovic P, Hogarth P, Barnes N, Kaslow D, Good M
Infect Immun
. 2000 Apr;
68(5):3019-22.
PMID: 10769007
Merozoite surface protein 1 (MSP-1(19)) is a leading malaria vaccine candidate. Specific antibodies contribute to immunity; binding to macrophages is believed to represent the main action of malaria antibodies. We...
9.
Rigby L, Epa V, Mackay G, Hulett M, Sutton B, Gould H, et al.
J Biol Chem
. 2000 Mar;
275(13):9664-72.
PMID: 10734118
The high affinity receptor for IgE, FcepsilonRI, binds IgE through the second Ig-like domain of the alpha subunit. The role of the first Ig-like domain is not well understood, but...
10.
Powell M, Barton P, Emmanouilidis D, Wines B, Neumann G, Peitersz G, et al.
Immunol Lett
. 1999 Jul;
68(1):17-23.
PMID: 10397151
Fc gamma RIIa is one of a family of specific cell surface receptors for immunoglobulin. Fc gamma RIIa, which binds immune complexes of certain IgG isotypes, plays important roles in...