P M Hinkle
Overview
Explore the profile of P M Hinkle including associated specialties, affiliations and a list of published articles.
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86
Citations
954
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Recent Articles
1.
Sattin A, Pekary A, Lloyd R, PAULSON M, Meyerhoff J, Hinkle P, et al.
Ann N Y Acad Sci
. 2003 Dec;
1003:458-60.
PMID: 14684488
No abstract available.
2.
Graves T, Patel S, Dannies P, Hinkle P
J Cell Sci
. 2001 Nov;
114(Pt 20):3685-94.
PMID: 11707520
In some individuals with autosomal dominant isolated growth hormone deficiency, one copy of growth hormone lacks amino acids 32-71 and is severely misfolded. We transfected COS7 cells with either wild-type...
3.
Smith J, Yu R, Hinkle P
Mol Endocrinol
. 2001 Aug;
15(9):1539-48.
PMID: 11518803
To determine whether the interaction of the TRH receptor with beta-arrestin is necessary for TRH activation of MAPK, cells expressing either intact or truncated, internalization-defective TRH receptors were transfected with...
4.
Rapoport A, Chen T, Sidell R, Luhowskyj S, Rosell K, Obrig T, et al.
Blood Cells Mol Dis
. 2001 Aug;
27(3):610-24.
PMID: 11482875
Burkitt's lymphoma cell lines have been important in vitro models for studying the pathogenesis of Burkitt's lymphoma (BL) and for exploring new treatment strategies. A new EBV(-) Burkitt's lymphoma cell...
5.
Romoser V, Graves T, Wu D, Jiang H, Hinkle P
Mol Endocrinol
. 2001 Jan;
15(1):125-35.
PMID: 11145744
These studies examined the importance of phospholipase Cbeta (PLCbeta) in the calcium responses of pituitary cells using PLCbeta3 knockout mice. Pituitary tissue from wild-type mice contained PLCbeta1 and PLCbeta3 but...
6.
Yu R, Hinkle P
J Biol Chem
. 2000 May;
275(31):23648-53.
PMID: 10811650
HEK293 cells expressing the thyrotropin-releasing hormone (TRH) receptor were transfected with cameleon Ca(2+) indicators designed to measure the free Ca(2+) concentration in the cytoplasm, [Ca(2+)](cyt), and the endoplasmic reticulum (ER),...
7.
Xie W, Samoriski G, McLaughlin J, Romoser V, Smrcka A, Hinkle P, et al.
Proc Natl Acad Sci U S A
. 1999 Sep;
96(18):10385-90.
PMID: 10468617
Morphine and other micro opioids regulate a number of intracellular signaling pathways, including the one mediated by phospholipase C (PLC). By studying PLC beta3-deficient mice, we have established a strong...
8.
Yu R, Hinkle P
J Biol Chem
. 1999 May;
274(22):15745-50.
PMID: 10336475
The thyrotropin-releasing hormone (TRH) receptor was expressed in embryonic fibroblasts from mice lacking the alpha subunits of Gq and G11 (Fq/11 cells) to determine whether G protein coupling is necessary...
9.
Fliss M, Hinkle P, Bancroft C
Mol Endocrinol
. 1999 Apr;
13(4):644-57.
PMID: 10194769
Previous studies have implied that a transcription factor(s) other than Pit-1 is involved in homeostatic regulation of PRL promoter activity via Pit-1-binding elements. One such element, 1P, was employed to...
10.
Yu R, Ashworth R, Hinkle P
Thyroid
. 1998 Nov;
8(10):887-94.
PMID: 9827655
Primary cultures of rat pituitary cells were stained with an antibody to the native thyrotropin-releasing hormone (TRH) receptor and with a bioactive, fluorescent analogue of TRH, Rhod-TRH. Rhod-TRH specifically stained...