P L Herrera
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Explore the profile of P L Herrera including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
863
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Recent Articles
1.
Cigliola V, Thorel F, Chera S, Herrera P
Diabetes Obes Metab
. 2016 Sep;
18 Suppl 1:87-96.
PMID: 27615136
The different forms of diabetes mellitus differ in their pathogenesis but, ultimately, they are all characterized by progressive islet β-cell loss. Restoring the β-cell mass is therefore a major goal...
2.
Herrera P
Diabetes Obes Metab
. 2009 Oct;
11 Suppl 4:91-6.
PMID: 19817792
To unravel the cellular and molecular mechanisms involved in beta-cell renewal and expansion throughout life, several different experimental models were devised in the past. A number of experimental approaches and...
3.
Riggs A, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, et al.
Diabetologia
. 2005 Oct;
48(11):2313-21.
PMID: 16215705
Aims/hypothesis: Wolfram syndrome is an autosomal recessive disorder characterised by childhood diabetes mellitus, optic atrophy and severe neurodegeneration, resulting in premature death. The aim of this study was to investigate...
4.
Herrera P, Wang H, Gjinovci A, Ishihara H, Wollheim C
Endocrinology
. 2001 Nov;
142(12):5311-20.
PMID: 11713231
Mutations in the transcription factor hepatocyte nuclear factor-1 alpha (HNF-1 alpha) cause maturity-onset diabetes of the young 3, a severe form of diabetes characterized by pancreatic beta-cell dysfunction. We have...
5.
Pepper M, Vassalli J, Herrera P
Nucleic Acids Res
. 2000 Nov;
28(23):E99.
PMID: 11095695
Experimental or therapeutic designs involving the conditional expression of genes often require the use of two different transgenes; this can represent a major undertaking. One of these systems takes advantage...
6.
Charollais A, Gjinovci A, Huarte J, Bauquis J, Nadal A, Martin F, et al.
J Clin Invest
. 2000 Jul;
106(2):235-43.
PMID: 10903339
Proper insulin secretion requires the coordinated functioning of the numerous beta cells that form pancreatic islets. This coordination depends on a network of communication mechanisms whereby beta cells interact with...
7.
Herrera P
Development
. 2000 May;
127(11):2317-22.
PMID: 10804174
To analyze cell lineage in the pancreatic islets, we have irreversibly tagged all the progeny of cells through the activity of Cre recombinase. Adult glucagon alpha and insulin beta cells...
8.
Gannon M, Herrera P, Wright C
Genesis
. 2000 Mar;
26(2):143-4.
PMID: 10686611
No abstract available.
9.
Herrera P, Harlan D, Vassalli P
Proc Natl Acad Sci U S A
. 2000 Jan;
97(1):279-84.
PMID: 10618409
Double transgenic mice [rat insulin promoter (RIP)-tumor necrosis factor (TNF) and RIP-CD80] whose pancreatic beta cells release TNF and bear CD80 all develop an acute early (6 wk) and lethal...
10.
Herrera P, Orci L, Vassalli J
Mol Cell Endocrinol
. 1998 Aug;
140(1-2):45-50.
PMID: 9722167
Ontogenic relationships between the different endocrine cell types of the islets of Langerhans were explored by generating transgenic mice, in which cells transcribing the glucagon, insulin, or pancreatic polypeptide genes...