P Ken Rose
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Explore the profile of P Ken Rose including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
247
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Recent Articles
1.
Maratta R, Fenrich K, Zhao E, Neuber-Hess M, Rose P
J Comp Neurol
. 2015 Mar;
523(11):1701-16.
PMID: 25728799
Serotonergic (5-HT) and noradrenergic (NA) input to spinal motoneurons is essential for generating plateau potentials and self-sustained discharges. Extensor motoneurons are densely innervated by 5-HT and NA synapses and have...
2.
Fenrich K, Zhao E, Wei Y, Garg A, Rose P
J Neurosci Methods
. 2014 Feb;
226:42-56.
PMID: 24487018
Background: Isolating specific cellular and tissue compartments from 3D image stacks for quantitative distribution analysis is crucial for understanding cellular and tissue physiology under normal and pathological conditions. Current approaches...
3.
Montague S, Fenrich K, Mayer-Macaulay C, Maratta R, Neuber-Hess M, Rose P
J Comp Neurol
. 2012 Jul;
521(3):638-56.
PMID: 22821606
The input-output properties of motoneurons are dynamically regulated. This regulation depends, in part, on the relative location of excitatory and inhibitory synapses, voltage-dependent and -independent channels, and neuromodulatory synapses on...
4.
Fenrich K, Rose P
J Comp Neurol
. 2011 Jun;
519(16):3240-58.
PMID: 21674488
We recently reported that some, but not all, axotomized propriospinal commissural interneurons (PCI) of the adult mammal can regenerate through spinal midsagittal transection injury sites (Fenrich and Rose [2009] J...
5.
Meehan C, MacDermid V, Montague S, Neuber-Hess M, Rose P
J Neurosci
. 2011 May;
31(18):6732-40.
PMID: 21543602
Axotomy can trigger profound alterations in the neuronal polarity of adult neurons in vivo. This can manifest itself in the development of new axon-like processes emanating from the tips of...
6.
Grande G, Bui T, Rose P
Brain Res
. 2010 Mar;
1333:9-27.
PMID: 20346350
Excitatory and inhibitory synapses may control neuronal output through a push-pull mechanism--that is, increases in excitation are coupled to simultaneous decreases in inhibition or vice versa. This pattern of activity...
7.
Fenrich K, Rose P
J Neurosci
. 2009 Oct;
29(39):12145-58.
PMID: 19793972
It is well established that long, descending axons of the adult mammalian spinal cord do not regenerate after a spinal cord injury (SCI). These axons do not regenerate because they...
8.
9.
Bui T, Grande G, Rose P
J Neurophysiol
. 2007 Nov;
99(2):571-82.
PMID: 18046007
The ability of inhibitory synaptic inputs to dampen the excitability of motoneurons is augmented when persistent inward currents (PICs) are activated. This amplification could be due to an increase in...
10.
Bui T, Grande G, Rose P
J Neurophysiol
. 2007 Nov;
99(2):583-94.
PMID: 18046006
In some motoneurons, L-type Ca2+ channels that partly mediate persistent inward currents (PICs) have been estimated to be arranged in 50- to 200-microm-long discrete regions in the dendrites, centered 100...