Giovanbattista Grande
Overview
Explore the profile of Giovanbattista Grande including associated specialties, affiliations and a list of published articles.
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11
Citations
207
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Recent Articles
1.
Yang Y, Fekete A, Arsenault J, Sengar A, Aitoubah J, Grande G, et al.
J Physiol
. 2024 Oct;
PMID: 39383250
Intersectin-1 (Itsn1) is a scaffold protein that plays a key role in coupling exocytosis and endocytosis of synaptic vesicles (SVs). However, it is unclear whether and how Itsn1 regulates these...
2.
Grande G, Negandhi J, Harrison R, Wang L
J Physiol
. 2014 Jan;
592(7):1581-600.
PMID: 24469075
Structure and function of central synapses are profoundly influenced by experience during developmental sensitive periods. Sensory synapses, which are the indispensable interface for the developing brain to interact with its...
3.
Grande G, Wang L
J Neurosci
. 2011 Sep;
31(38):13386-99.
PMID: 21940432
Reliable neuronal spiking is critical for a myriad of computations performed by neural circuits. This is particularly evident for sound localization cues in the auditory brainstem circuits that detect timing...
4.
5.
Yang Y, Fedchyshyn M, Grande G, Aitoubah J, Tsang C, Xie H, et al.
Neuron
. 2010 Jul;
67(1):100-15.
PMID: 20624595
Neurotransmitter release depends critically on close spatial coupling of Ca(2+) entry to synaptic vesicles at the nerve terminal; however, the molecular substrates determining their physical proximity are unknown. Using the...
6.
Grande G, Bui T, Rose P
Brain Res
. 2010 Mar;
1333:9-27.
PMID: 20346350
Excitatory and inhibitory synapses may control neuronal output through a push-pull mechanism--that is, increases in excitation are coupled to simultaneous decreases in inhibition or vice versa. This pattern of activity...
7.
Bui T, Grande G, Rose P
J Neurophysiol
. 2007 Nov;
99(2):571-82.
PMID: 18046007
The ability of inhibitory synaptic inputs to dampen the excitability of motoneurons is augmented when persistent inward currents (PICs) are activated. This amplification could be due to an increase in...
8.
Bui T, Grande G, Rose P
J Neurophysiol
. 2007 Nov;
99(2):583-94.
PMID: 18046006
In some motoneurons, L-type Ca2+ channels that partly mediate persistent inward currents (PICs) have been estimated to be arranged in 50- to 200-microm-long discrete regions in the dendrites, centered 100...
9.
Grande G, Bui T, Rose P
J Physiol
. 2007 Jul;
583(Pt 2):611-30.
PMID: 17615105
Previous studies show that the activation of voltage-dependent channels is dependent on the local density of synapses in the dendritic region containing voltage-dependent channels. We hypothesized that the selective innervation...
10.
Grande G, Bui T, Rose P
J Neurophysiol
. 2007 Apr;
97(6):4023-35.
PMID: 17428909
In the presence of monoamines, L-type Ca(2+) channels on the dendrites of motoneurons contribute to persistent inward currents (PICs) that can amplify synaptic inputs two- to sixfold. However, the exact...