P J Shiromani
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Explore the profile of P J Shiromani including associated specialties, affiliations and a list of published articles.
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50
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1147
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Recent Articles
1.
Zhang S, Lin L, Kaur S, Thankachan S, Blanco-Centurion C, Yanagisawa M, et al.
Neuroscience
. 2007 Jul;
148(1):34-43.
PMID: 17618058
Narcolepsy is linked to a widespread loss of neurons containing the neuropeptide hypocretin (HCRT), also named orexin. A transgenic (TG) rat model has been developed to mimic the neuronal loss...
2.
Blanco-Centurion C, Shiromani P
Neurobiol Aging
. 2005 Nov;
27(12):1859-69.
PMID: 16309796
With aging there is a significant decline in the normal architecture of sleep and a reduction in the diurnal amplitude of core body temperature. Regular moderate exercise has been shown...
3.
Gerashchenko D, Blanco-Centurion C, Miller J, Shiromani P
Neuroscience
. 2005 Nov;
137(1):29-36.
PMID: 16289583
The neuropeptide hypocretin, also known as orexin, has been implicated in waking since its deletion leads to the sleep disorder narcolepsy. Hypocretin neurons project to major arousal areas, and in...
4.
Murillo-Rodriguez E, Blanco-Centurion C, Gerashchenko D, Salin-Pascual R, Shiromani P
Neuroscience
. 2003 Dec;
123(2):361-70.
PMID: 14698744
There are significant decrements in sleep with age. These include fragmentation of sleep, increased wake time, decrease in the length of sleep bouts, decrease in the amplitude of the diurnal...
5.
Goulet M, Shiromani P, Ware C, Strong R, Boismenu R, Rusche J
Neuroscience
. 2003 May;
118(4):881-8.
PMID: 12732234
For the last 100 years secretin has been extensively studied for its hormonal effects on digestion. Recent observations that the deficits in social reciprocity skills seen in young (3-4-year-old) autistic...
6.
Gerashchenko D, Blanco-Centurion C, Greco M, Shiromani P
Neuroscience
. 2003 Jan;
116(1):223-35.
PMID: 12535955
Narcolepsy, a disabling neurological disorder characterized by excessive daytime sleepiness, sleep attacks, sleep fragmentation, cataplexy, sleep-onset rapid eye movement sleep periods and hypnagogic hallucinations was recently linked to a loss...
7.
Salin-Pascual R, Gerashchenko D, Greco M, Blanco-Centurion C, Shiromani P
Neuropsychopharmacology
. 2001 Oct;
25(5 Suppl):S21-7.
PMID: 11682269
The recent discovery linking narcolepsy, a sleep disorder characterized by very short REM sleep latency, with a neuropeptide that regulates feeding and energy metabolism, provides a way to understand how...
8.
Gerashchenko D, Kohls M, Greco M, Waleh N, Salin-Pascual R, Kilduff T, et al.
J Neurosci
. 2001 Sep;
21(18):7273-83.
PMID: 11549737
Hypocretins (Hcrts) are recently discovered peptides linked to the human sleep disorder narcolepsy. Humans with narcolepsy have decreased numbers of Hcrt neurons and Hcrt-null mice also have narcoleptic symptoms. Hcrt...
9.
Gerashchenko D, Salin-Pascual R, Shiromani P
Brain Res
. 2001 Sep;
913(1):106-15.
PMID: 11532254
Neurons containing the peptide hypocretin, also known as orexin, were recently implicated in the human sleep disorder narcolepsy. Hypocretin neurons are located only in the lateral hypothalamus from where they...
10.
Wagner D, Salin-Pascual R, Greco M, Shiromani P
Sleep Res Online
. 2001 May;
3(1):35-42.
PMID: 11382898
The present study investigated the distribution of neurons implicated in the regulation of sleep in three species generally used in sleep research, i.e., mice, rats and cats. We focused on...