P J Hughes
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Explore the profile of P J Hughes including associated specialties, affiliations and a list of published articles.
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112
Citations
1359
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Recent Articles
11.
Harris R, Wood D, Bottomley L, Blagg S, Owen K, Hughes P, et al.
J Clin Endocrinol Metab
. 2004 Apr;
89(4):1779-87.
PMID: 15070945
We investigated the ability of 37 flavonoids and flavonoid sulfoconjugates, including some abundant dietary constituents, to act as substrates and/or inhibitors of the sulfotransferase and sulfatase enzymes that interconvert active...
12.
Hughes P, Evans R, Miller B, Goldberg J, Sonnabend D, Walsh W
Knee Surg Sports Traumatol Arthrosc
. 2003 Dec;
13(1):55-9.
PMID: 14689169
The reconstruction of a tendon-bone interface, as in rotator-cuff repairs, remains a challenging surgical problem. There is however, little data to show what effect joint position or repair loading under...
13.
Hughes P, Hagan R, Fisher A, Holt E, Frostick S
Am J Sports Med
. 2001 Dec;
29(6):738-45.
PMID: 11734487
An apparatus has been developed to enable the in vitro measurement of the kinematics and kinetics of a slipknot, both while the knot is being tightened and with the knot...
14.
Bajaj N, Rose P, Hughes P
Acta Neurol Scand
. 2001 Oct;
104(4):239-42.
PMID: 11589654
Both acute transverse myelitis (ATM) and Guillain-Barré syndrome (GBS) occur as rare associations with mumps viraemia but to our knowledge, concurrent ATM and GBS related to mumps has only been...
15.
Boonyakiat Y, Hughes P, Ghazi F, Stanway G
J Virol
. 2001 Sep;
75(20):10000-4.
PMID: 11559835
The human parechovirus 1 RGD motif in VP1 was studied by mutagenesis. An RGD-to-RGE change gave only revertant viruses with a restored RGD, while deletion of GD was lethal and...
16.
Kirk C, Harris R, Wood D, Waring R, Hughes P
Biochem Soc Trans
. 2001 May;
29(Pt 2):209-16.
PMID: 11356156
Phytoestrogens are natural constituents of our diets that have been suggested to protect against hormone-dependent breast cancer. Some of the diverse effects of these compounds may be attributed to ligand-dependent...
17.
Hughes P
J R Nav Med Serv
. 2001 May;
86(3):120-2.
PMID: 11346920
A case of internal carotid artery occlusion following a sports dive is described. The investigation and management of this condition is discussed with particular reference to blunt trauma being a...
18.
Hughes P, Twist L, Durham J, Choudhry M, Drayson M, Chandraratna R, et al.
Biochem J
. 2001 Apr;
355(Pt 2):361-71.
PMID: 11284723
HL60 promyeloid cells express both classes of oestrogen receptor (ERalpha and ERbeta). We show that hydrolysis of oestrone sulphate by steroid sulphatase is a major source of oestrone in HL60...
19.
Hughes P, MacKay P
Anaesth Intensive Care
. 2001 Mar;
29(1):79-80.
PMID: 11261921
No abstract available.
20.
Hughes P, McLellan H, Lowes D, Kahn S, Bilmen J, Tovey S, et al.
Biochem Biophys Res Commun
. 2000 Nov;
277(3):568-74.
PMID: 11061995
Industrial alkylphenols in the environment may act as "xenoestrogens" to disrupt testicular development and decrease male fertility. Amongst possible targets for these compounds are testicular Sertoli cells, which nurture the...