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P Henklein

Explore the profile of P Henklein including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 1695
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Recent Articles
1.
Bialy L, Kuckelkorn U, Henklein P, Fayet J, Wilczynski G, Kaminski A, et al.
Histol Histopathol . 2018 Sep; 34(4):359-372. PMID: 30226264
Extralysosomal proteolysis is a multistep process involving the Ubiquitin- Proteasome System (UPS) and supplementary peptidases. Tripeptidyl peptidase II (TPPII) is the most extensively characterized enzyme, supplementing and sometimes substituting for...
2.
Ebstein F, Textoris-Taube K, Keller C, Golnik R, Vigneron N, Van den Eynde B, et al.
Sci Rep . 2016 Apr; 6:24032. PMID: 27049119
Proteasome-catalyzed peptide splicing represents an additional catalytic activity of proteasomes contributing to the pool of MHC-class I-presented epitopes. We here biochemically and functionally characterized a new melanoma gp100 derived spliced...
3.
Schade R, Henklein P, Harms C, Jonas L, Lautenschlager M, Schoneberg T, et al.
Altern Lab Anim . 2014 Aug; 28(4):575-601. PMID: 25144929
No abstract available.
4.
Ebner F, Hepworth M, Rausch S, Janek K, Niewienda A, Kuhl A, et al.
Allergy . 2014 Jul; 69(11):1489-97. PMID: 25069662
Background: Gastrointestinal nematodes are currently being evaluated as a novel therapeutic in the treatment of chronic human inflammatory disorders, due to their unique ability to induce immunoregulatory pathways in their...
5.
Chanturiya A, Basanez G, Schubert U, Henklein P, Yewdell J, Zimmerberg J
J Virol . 2004 May; 78(12):6304-12. PMID: 15163724
A frameshifted region of the influenza A virus PB1 gene encodes a novel protein, termed PB1-F2, a mitochondrial protein that can induce cell death. Many proapoptotic proteins are believed to...
6.
Kaufmann R, Junker U, Nuske K, Westermann M, Henklein P, Scheele J, et al.
Int J Oncol . 2001 Dec; 20(1):177-80. PMID: 11743661
In this study, we report coexpression of proteinase-activated receptor (PAR)-1- and PAR-3-type thrombin receptors in primary cultures obtained from surgically resected specimens of renal cell carcinomas (RCCs). Receptor expression on...
7.
Chen W, Calvo P, Malide D, Gibbs J, Schubert U, Bacik I, et al.
Nat Med . 2001 Dec; 7(12):1306-12. PMID: 11726970
While searching for alternative reading-frame peptides encoded by influenza A virus that are recognized by CD8+ T cells, we found an abundant immunogenic peptide encoded by the +1 reading frame...
8.
Kuon W, Holzhutter H, Appel H, Grolms M, Kollnberger S, Traeder A, et al.
J Immunol . 2001 Oct; 167(8):4738-46. PMID: 11591805
The association of HLA-B27 with ankylosing spondylitis and reactive arthritis is the strongest one known between an MHC class I Ag and a disease. We have searched the proteome of...
9.
Goodfellow B, Dias J, Ferreira G, Henklein P, Wray V, Macedo A
FEBS Lett . 2001 Sep; 505(2):325-31. PMID: 11566198
The mitochondrial import of 5-aminolevulinate synthase (ALAS), the first enzyme of the mammalian heme biosynthetic pathway, requires the N-terminal presequence. The 49 amino acid presequence transit peptide (psALAS) for murine...
10.
Knuehl C, Spee P, Ruppert T, Kuckelkorn U, Henklein P, Neefjes J, et al.
J Immunol . 2001 Jul; 167(3):1515-21. PMID: 11466372
The 20S proteasome is involved in the processing of MHC class I-presented Ags. A number of epitopes is known to be generated as precursor peptides requiring trimming either before or...