P H Steenbergh
Overview
Explore the profile of P H Steenbergh including associated specialties, affiliations and a list of published articles.
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36
Citations
567
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Recent Articles
1.
Hamelers I, Steenbergh P
Endocr Relat Cancer
. 2003 Jun;
10(2):331-45.
PMID: 12790794
Estrogens and insulin-like growth factors (IGFs) act as mitogens promoting cell proliferation in normal breast tissue as well as in breast carcinomas. Both hormones have been shown to play a...
2.
Dufourny B, van Teeffelen HA , Hamelers I, Sussenbach J, Steenbergh P
J Endocrinol
. 2000 Aug;
166(2):329-38.
PMID: 10927622
Treatment of quiescent MCF-7 human breast cancer cells with either the polypeptide growth factors insulin-like growth factor-I (IGF-I) or epidermal growth factor (EGF), the steroid hormone estradiol (E2) or the...
3.
Meton I, Boot E, Sussenbach J, Steenbergh P
FEBS Lett
. 1999 Mar;
444(2-3):155-9.
PMID: 10050749
Salmon insulin-like growth factor-I (sIGF-I) expression is, as in mammals, induced by growth hormone (GH). To elucidate the mechanism by which GH stimulates the transcription of the IGF-I gene, we...
4.
Barreca A, Bozzola M, Cesarone A, Steenbergh P, Holthuizen P, Severi F, et al.
J Clin Endocrinol Metab
. 1998 Oct;
83(10):3534-41.
PMID: 9768660
We report a case of short stature associated with high circulating levels of insulin-like growth factor (IGF)-binding protein-1 (IGFBP-10 and low levels of IGF-II responsive to pharmacological treatment with GH....
5.
Alblas J, Steenbergh P, Sussenbach J, van der Burg B
Oncogene
. 1998 Feb;
16(1):131-9.
PMID: 9467952
In MCF7 breast cancer cells, mitogen-activated protein (MAP) kinase (i.e. Erk-1/2) is activated by the mitogen insulin, but also by the growth inhibiting agent TPA, though with very different kinetics....
6.
Dufourny B, Alblas J, van Teeffelen H, van Schaik F, van der Burg B, Steenbergh P, et al.
J Biol Chem
. 1998 Jan;
272(49):31163-71.
PMID: 9388270
Addition of insulin-like growth factor I (IGF-I) to quiescent breast tumor-derived MCF-7 cells causes stimulation of cyclin D1 synthesis, hyperphosphorylation of the retinoblastoma protein pRb, DNA synthesis, and cell division....
7.
Nolten L, Steenbergh P, Sussenbach J
J Biol Chem
. 1996 Dec;
271(50):31846-54.
PMID: 8943227
Promoter 1 (P1) of the human insulin-like growth factor I (IGF-I) gene is most active in adult liver. In this study we show that HNF-3beta, a member of the winged...
8.
Nolten L, Steenbergh P, Sussenbach J
Mol Endocrinol
. 1995 Nov;
9(11):1488-99.
PMID: 8584026
Expression of the human insulin-like growth factor I (hIGF-I) gene is regulated in a tissue- and developmental stage-specific manner. The hIGF-I gene has two promoters, P1 and P2. P1 is...
9.
Kulik V, Kavsan V, van Schaik F, Nolten L, Steenbergh P, Sussenbach J
J Biol Chem
. 1995 Jan;
270(3):1068-73.
PMID: 7836361
Hepatocyte nuclear factor 1 (HNF-1) was found to have a potent stimulatory action on the activity of the promoter of the salmon insulin-like growth factor I (IGF-I) gene in transient...
10.
Nolten L, van Schaik F, Steenbergh P, Sussenbach J
Mol Endocrinol
. 1994 Dec;
8(12):1636-45.
PMID: 7708053
The expression of the human insulin-like growth factor I (hIGF-I) gene is regulated in a developmental stage- and tissue-specific manner. Postnatally, the liver becomes the main endocrine source of this...