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P H Ray

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Articles 38
Citations 576
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Recent Articles
1.
Smith G, Banks S, Blumenkopf T, Cory M, Humphreys J, Laethem R, et al.
J Biol Chem . 1997 Jun; 272(25):15804-16. PMID: 9188478
Antibody-directed enzyme prodrug therapy (ADEPT) has the potential of greatly enhancing antitumor selectivity of cancer therapy by synthesizing chemotherapeutic agents selectively at tumor sites. This therapy is based upon targeting...
2.
Laethem R, Blumenkopf T, Cory M, Elwell L, Moxham C, Ray P, et al.
Arch Biochem Biophys . 1996 Aug; 332(1):8-18. PMID: 8806703
We are investigating the potential utility of human carboxypeptidases A in antibody-directed enzyme prodrug therapy (ADEPT). Hybridization screening of a human pancreatic cDNA library with cDNA probes that encoded either...
3.
Wilson J, Wright L, Martin J, Haire S, Ray P, Painter G, et al.
J Acquir Immune Defic Syndr Hum Retrovirol . 1996 Jan; 11(1):20-30. PMID: 8528729
Recombinant wild type (wt) and T215Y HIV-1 reverse transcriptase (RT) were isolated using three methods designated A, B, and C. The three samples of wt RT were kinetically indistinguishable with...
4.
Stammers D, Somers D, Ross C, Kirby I, Ray P, Wilson J, et al.
J Mol Biol . 1994 Sep; 242(4):586-8. PMID: 7523679
Reverse transcriptase (RT) from the human immunodeficiency virus type 1 has been crystallized in four closely related forms, the best of which diffract X-rays to 2.2 A resolution. The RT...
5.
Rosemond M, Strobel S, Ray P, Bassford Jr P
FEBS Lett . 1994 Aug; 349(2):281-5. PMID: 8050582
Maltose-binding protein (MBP), whose export in E. coli is dependent upon the chaperone SecB, and ribose-binding protein (RBP), whose export is SecB-independent, have been used to generate hybrid secretory proteins....
6.
Talarico T, Barkocy-Gallagher G, Ray P, Bassford Jr P
Biochem Biophys Res Commun . 1993 Dec; 197(3):1154-66. PMID: 8280130
Processing of 37 precursor maltose-binding protein (preMBP) species by purified signal peptidase I (SPase I) was assayed. The in vitro reaction was inefficient compared to processing in Escherichia coli cells....
7.
Dallas W, Dev I, Ray P
J Bacteriol . 1993 Dec; 175(23):7743-4. PMID: 8244950
No abstract available.
8.
Rush J, Shelling J, Zingg N, Ray P, Waechter C
J Biol Chem . 1993 Jun; 268(18):13110-7. PMID: 8514752
The specificity of Man-P-Dol:Man5-8GlcNAc2-P-P-Dol (Oligo-P-P-Dol) mannosyltransferase activity in pig brain was investigated by comparing a variety of mannosylphosphorylisoprenols as mannosyl donors. For this comparison the beta-Man-P-isoprenols were synthesized using a...
9.
Dallas W, Gowen J, Ray P, Cox M, Dev I
J Bacteriol . 1992 Sep; 174(18):5961-70. PMID: 1522070
The Escherichia coli gene coding for dihydropteroate synthase (DHPS) has been cloned and sequenced. The protein has 282 amino acids and a compositional molecular mass of 30,314 daltons. Increased expression...
10.
Talarico T, Ray P, Dev I, Merrill B, Dallas W
J Bacteriol . 1992 Sep; 174(18):5971-7. PMID: 1325970
The gene coding for the Escherichia coli enzyme 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase has been cloned and sequenced. This gene, designated folK, codes for a protein of 159 amino acids, including an amino-terminal methionine....