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P H Pak

Explore the profile of P H Pak including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 637
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Recent Articles
1.
Wittstein I, Kass D, Pak P, Maughan W, Fetics B, Hare J
J Am Coll Cardiol . 2001 Aug; 38(2):429-35. PMID: 11499734
Objectives: This study tested the hypothesis that angiotensin-converting enzyme (ACE) inhibitors attenuate beta-adrenergic contractility in patients with idiopathic dilated cardiomyopathy (DCM) through nitric oxide (NO) myocardial signaling. Background: The ACE...
2.
Pak P, Maughan W, Baughman K, Kieval R, Kass D
Circulation . 1998 Aug; 98(3):242-8. PMID: 9697824
Background: Dual-chamber pacing can improve symptoms in hypertrophic cardiomyopathy (HCM), but the mechanism remains unclear. We hypothesized that pacing generates discoordinate contraction and a rightward shift of the end-systolic pressure-volume...
3.
Senzaki H, Gluzband Y, Pak P, Crow M, Janicki J, Kass D
Circ Res . 1998 Mar; 82(4):503-12. PMID: 9506711
Synergistic interaction between angiotensin II (Ang II) and evolving cardiodepression may play an important role in worsening chamber function, particularly in diastole. To test this hypothesis, Ang II was infused...
4.
Chen C, Nevo E, Fetics B, Nakayama M, Pak P, Maughan W, et al.
Am J Cardiol . 1997 Oct; 80(6):756-61. PMID: 9315583
Automated border detection enables real-time tracking of left ventricular (LV) volume by 2-dimensional transthoracic echocardiography. This technique has not been previously compared with simultaneously measured continuous LV volumes at rest...
5.
Pak P, Nuss H, Tunin R, Kaab S, Tomaselli G, Marban E, et al.
J Am Coll Cardiol . 1997 Aug; 30(2):576-84. PMID: 9247535
Objectives: This study sought to determine whether the canine model of tachycardia-induced heart failure (HF) is an effective model for sudden cardiac death (SCD) in HF. Background: Such a well...
6.
Chen C, Nevo E, Fetics B, Pak P, Yin F, Maughan W, et al.
Circulation . 1997 Apr; 95(7):1827-36. PMID: 9107170
Background: Central aortic pressures and waveform convey important information about cardiovascular status, but direct measurements are invasive. Peripheral pressures can be measured noninvasively, and although they often differ substantially from...
7.
Pak P, Maughan L, Baughman K, Kass D
Circulation . 1996 Jul; 94(1):52-60. PMID: 8964117
Background: Dynamic diastolic pressure-volume curves measured during filling (PVR fill) in patients with idiopathic hypertrophic cardiomyopathy (HCM) are often considerably shallower than would be anticipated if one assumed high chamber...
8.
Kaab S, Nuss H, Chiamvimonvat N, ORourke B, Pak P, Kass D, et al.
Circ Res . 1996 Feb; 78(2):262-73. PMID: 8575070
Membrane current abnormalities have been described in human heart failure. To determine whether similar current changes are observed in a large animal model of heart failure, we studied dogs with...
9.
Feldman M, Pak P, Wu C, Haber H, Heesch C, BERGIN J, et al.
Circulation . 1996 Feb; 93(3):474-83. PMID: 8565164
Background: OPC-18790 is a water-soluble quinolinone derivative that shares the pharmacological properties of vesnarinone and that may be useful for treating heart failure. We studied the contribution and relative dose...
10.
Pak P, Gillinov A, Hruban R, Rosenthal L, Rosengard B, Augustine S, et al.
J Heart Lung Transplant . 1995 Sep; 14(5):1003-5. PMID: 8800711
Ascending aortic dissection is rare in cardiac allograft recipients. Only two patients with dissection arising from the native aorta have been reported previously and, unfortunately, the diagnosis was made postmortem...