P H Naccache
Overview
Explore the profile of P H Naccache including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
146
Citations
1985
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Desaulniers P, Fernandes M, Gilbert C, Bourgoin S, Naccache P
J Leukoc Biol
. 2001 Oct;
70(4):659-68.
PMID: 11590204
The inflammatory response in acute gouty arthritis is in large part a result of the interaction between neutrophils and monosodium urate (MSU) crystals. The tyrosine kinase Syk, which has been...
2.
Gilbert C, Barabe F, Bourgoin S, McColl S, Damaj B, Naccache P
J Immunol
. 2001 Mar;
166(7):4664-71.
PMID: 11254726
SAM68 (Src-associated in mitosis 68 kDa) is a member of the signal transduction of activator RNA novel gene family coding for proteins postulated to be involved in signal transduction and...
3.
Garceau V, Houle M, Chouinard F, Gagnon S, Harbour D, Naccache P, et al.
J Immunol Methods
. 2001 Feb;
249(1-2):121-36.
PMID: 11226470
ADP-ribosylation factors (Arf) are small GTP-binding proteins involved in vesicular transport and the activation of phospholipase D (PLD). The conversion of Arf-GDP to Arf-GTP is promoted in vivo by guanine...
4.
Naccache P, Levasseur S, Lachance G, Chakravarti S, Bourgoin S, McColl S
J Biol Chem
. 2000 May;
275(31):23636-41.
PMID: 10816567
The activation of human polymorphonuclear neutrophil leukocytes (neutrophils) is associated with an increased synthesis of the highly phosphorylated phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3)). The aims of the present investigation were to determine...
5.
Thibault N, Harbour D, Borgeat P, Naccache P, Bourgoin S
Blood
. 2000 Jan;
95(2):519-27.
PMID: 10627457
Adenosine (Ado) is an important autocrine modulator of neutrophil functions. In this study, we determined the effects of endogenous Ado on fMet-Leu-Phe (fMLP)-induced phospholipase D (PLD) activity in neutrophils. The...
6.
Gilbert C, Naccache P
J Immunol
. 2000 Jan;
164(2):1020-8.
PMID: 10623852
The interplay between serine/threonine and tyrosine phosphorylation was studied in human neutrophils. The direct effects of calyculin and okadaic acid, potent inhibitors of PP1 and PP2A serine/threonine phosphatases, on the...
7.
Houle M, Naccache P, Bourgoin S
J Leukoc Biol
. 1999 Dec;
66(6):1021-30.
PMID: 10614786
We focus on the mechanisms of regulation of phospholipase D (PLD) activity. Three agonists known to stimulate PLD activity, fMet-Leu-Phe (fMLP), phorbol 12-myristate 13-acetate (PMA) and V4+-OOH, induced a differential...
8.
Berkova N, Gilbert C, Goupil S, Yan J, Korobko V, Naccache P
J Immunol
. 1999 May;
162(10):6226-32.
PMID: 10229868
Haptoglobin (Hp), TNF-alpha, and neutrophils are parts of a highly interactive ensemble participating in inflammatory processes. Hp is taken up by neutrophils, stored within a cytoplasmic granular compartment, and is...
9.
Al-Shami A, Naccache P
J Biol Chem
. 1999 Feb;
274(9):5333-8.
PMID: 10026141
Granulocyte-macrophage colony-stimulating factor (GM-CSF) regulates many of the biological activities of human neutrophils. The signaling pathways via which these effects are mediated are not fully understood. We have shown previously...
10.
Marcil J, Harbour D, Houle M, Naccache P, Bourgoin S
Biochem J
. 1999 Jan;
337 ( Pt 2):185-92.
PMID: 9882614
Protein kinase Calpha (PKCalpha) and small GTPases of the Rho and ADP-ribosylation factor (Arf) family are implicated in the regulation of phospholipase D1 (PLD1) activity. Although they are involved in...