P H Hackett
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Explore the profile of P H Hackett including associated specialties, affiliations and a list of published articles.
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42
Citations
1121
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Recent Articles
1.
Hackett P, Yarnell P, Weiland D, Reynard K
AJNR Am J Neuroradiol
. 2019 Jan;
40(3):464-469.
PMID: 30679208
MR imaging of high-altitude cerebral edema shows reversible WM edema, especially in the corpus callosum and subcortical WM. Recent studies have revealed hemosiderin deposition in WM long after high-altitude cerebral...
2.
Schoene R, Roach R, Lahiri S, Peters Jr R, Hackett P, Santolaya R
Am J Hum Biol
. 2017 May;
2(6):663-668.
PMID: 28520127
No abstract available.
3.
Roach R, Hackett P
J Exp Biol
. 2001 Oct;
204(Pt 18):3161-70.
PMID: 11581330
Traditionally, scientists and clinicians have explored peripheral physiological responses to acute hypoxia to explain the pathophysiological processes that lead to acute mountain sickness (AMS) and high-altitude cerebral edema (HACE). After...
4.
5.
Hackett P
High Alt Med Biol
. 2001 Mar;
1(4):337-9.
PMID: 11256470
A 31-year-old man suffered diplopia and ataxia on two occasions when he ascended from sea level to 4,000 m. Evaluation revealed a moderate-sized subarachnoid cyst in the left frontal region,...
6.
Yarnell P, Heit J, Hackett P
Semin Neurol
. 2000 Aug;
20(2):209-17.
PMID: 10946741
High-altitude cerebral edema (HACE) is a potentially fatal metabolic encephalopathy associated with a time-dependent exposure to the hypobaric hypoxia of altitude. Symptoms commonly are headache, ataxia, and confusion progressing to...
7.
Hackett P
Adv Exp Med Biol
. 2000 Jan;
474:23-45.
PMID: 10634991
The diagnosis, treatment and prevention of high altitude cerebral edema (HACE) are fairly well established. The major unresolved issues are 1) the pathophysiology, 2) the individual susceptibility, and 3) the...
8.
Hackett P
Wilderness Environ Med
. 1999 Aug;
10(2):97-109.
PMID: 10442158
Despite normal cerebral oxygenation and normal global cerebral metabolism, vasogenic edema develops in humans (and sheep) who become moderately ill with AMS/ HACE during 24 hr or more of hypoxic...
9.
Roach R, Greene E, Schoene R, Hackett P
Aviat Space Environ Med
. 1998 Dec;
69(12):1182-5.
PMID: 9856544
Background: Acute mountain sickness (AMS) is a usually self-limiting syndrome encompassing headache, nausea and dizziness. AMS is seen in those that go from low to high altitudes too quickly, without...
10.
Hackett P, Yarnell P, Hill R, Reynard K, Heit J, McCormick J
JAMA
. 1998 Dec;
280(22):1920-5.
PMID: 9851477
Context: Because of its onset in generally remote environments, high-altitude cerebral edema (HACE) has received little scientific attention. Understanding the pathophysiology might have implications for prevention and treatment of both...