P H Cobbold
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Explore the profile of P H Cobbold including associated specialties, affiliations and a list of published articles.
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56
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983
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Recent Articles
1.
Woods N, Dixon C, Yasumoto T, Cuthbertson K, Cobbold P
Cell Signal
. 2000 Jan;
11(11):805-11.
PMID: 10617283
We report the results using bioluminescent and fluorescent indicators to investigate maitotoxin-induced free Ca changes in single rat hepatocytes. Maitotoxin generated a steadily rising free Ca increase after a long...
2.
Green A, Cobbold P, Dixon C
Cell Calcium
. 1999 May;
25(2):173-8.
PMID: 10326684
Single rat hepatocytes, microinjected with the Ca(2+)-sensitive photoprotein aequorin, respond to agonists acting through the phosphoinositide signalling pathway by the generation of oscillations in cytosolic free Ca2+ concentration ([Ca2+]i). The...
3.
Bratten C, Cobbold P, Cooper J
Anal Chem
. 1998 Apr;
70(6):1164-70.
PMID: 9530006
To study the cellular events surrounding the formation of purines in cardiac ischemia, we have micromachined a micrometer-scale titer chamber containing an integrated electrochemical sensor, capable of measuring analytes produced...
4.
Green A, Cobbold P, Dixon C
Cell Calcium
. 1997 Aug;
22(2):99-109.
PMID: 9292228
Single rat hepatocytes, microinjected with the Ca(2+)-sensitive photoprotein aequorin, respond to agonists acting through the phosphoinositide signalling pathway by the generation of oscillations in cytosolic free Ca2+ concentration ([Ca2+]i). The...
5.
Greenwood M, Varela-Nieto I, Marrero I, Gil B, Mato J, Cobbold P
Cell Calcium
. 1997 Feb;
21(2):125-33.
PMID: 9132295
Inositol-phosphoglycan (IPG) is a putative mediator of insulin action that has been shown to affect numerous biochemical processes. IPG, prepared from liver membranes, promptly inhibited phenylephrine- or vasopressin-induced [Ca2+]i oscillations...
6.
Dementeva E, Ugarova N, Cobbold P
Biokhimiia
. 1996 Jul;
61(7):1285-93.
PMID: 9035741
Recombinant firefly luciferase was expressed in E. coli and its properties inside the intact cells were studied. At low concentrations, antibiotic polymyxin B increases permeability of E. coli cell membrane...
7.
Marrero I, Green A, Cobbold P, Dixon C
Biochem J
. 1996 Jan;
313 ( Pt 2):525-8.
PMID: 8573087
Single rat hepatocytes microinjected with the photoprotein aequorin generate oscillations in the cytosolic free Ca2+ concentration ([Ca2+]i) when stimulated with agonists acting through the phosphoinositide signalling pathway. We show here...
8.
Dixon C, Cobbold P, Green A
Br J Pharmacol
. 1995 Oct;
116(3):1979-84.
PMID: 8640335
1. Aequorin-injected, single rat hepatocytes generate series of repetitive transients in cytosolic free calcium concentration ([Ca2+]i) when stimulated with agonists acting through the phosphoinositide signalling pathway, including ADP and ATP....
9.
Berrie C, Cobbold P
Cell Calcium
. 1995 Sep;
18(3):232-44.
PMID: 8529264
In single isolated rat hepatocytes Ca(2+)-mobilising hormones induce oscillations in cytosolic free Ca2+ ([Ca2+]i) in which the frequency of spiking depends on agonist dose, but the time course of individual...
10.
Green A, Cobbold P, Dixon C
Biochem J
. 1995 Sep;
310 ( Pt 2):629-35.
PMID: 7654204
Diadenosine 5',5"'-P1,P3-triphosphate (Ap3A) and diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) induce distinctive patterns of [Ca2+]i oscillations in single rat hepatocytes. We show here that [Ca2+]i oscillations induced by Ap3A and ADP are indistinguishable...