P G Steinherz
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Explore the profile of P G Steinherz including associated specialties, affiliations and a list of published articles.
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87
Citations
1240
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Recent Articles
11.
Trigg M, Steinherz P, Chappell R, Johnstone H, Gaynon P, Kersey J, et al.
J Pediatr Hematol Oncol
. 2000 Mar;
22(1):27-33.
PMID: 10695818
Purpose: Children with acute lymphoblastic leukemia (ALL) who had bulky disease (lymphomatous features) at diagnosis had the highest rate of testicular relapse (20%) of any ALL subgroup on previous Children's...
12.
Frangoul H, Ames M, Mosher R, Reid J, Krailo M, Seibel N, et al.
Clin Cancer Res
. 2000 Jan;
5(12):3956-62.
PMID: 10632325
The purpose of this study was to determine the toxicity, maximum tolerated dose, and pharmacokinetics of a 21-day continuous infusion of topotecan in children with relapsed solid tumors. Fifteen patients...
13.
Heerema N, Nachman J, Sather H, Sensel M, Lee M, Hutchinson R, et al.
Blood
. 1999 Dec;
94(12):4036-45.
PMID: 10590047
We have determined the prognostic significance of hypodiploidy (<46 chromosomes) in a large cohort of children with acute lymphoblastic leukemia (ALL) treated by the Children's Cancer Group. Among 1,880 patients,...
14.
Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia
Sun L, Goodman P, Wood C, Crotty M, Sensel M, Sather H, et al.
J Clin Oncol
. 1999 Nov;
17(12):3753-66.
PMID: 10577847
Purpose: We sought to determine if molecular abnormalities involving the Ikaros gene could contribute to the development of acute lymphoblastic leukemia (ALL) in children. Patients And Methods: We studied Ikaros...
15.
Heerema N, Sather H, Sensel M, Lange B, Bostrom B, Nachman J, et al.
Blood
. 1999 Sep;
94(5):1537-44.
PMID: 10477677
Cytogenetic abnormalities of chromosome arm 9p occur frequently in children with acute lymphoblastic leukemia (ALL). We analyzed 201 such cases (11%) in 1,839 children with newly diagnosed ALL treated between...
16.
Sun L, Crotty M, Sensel M, Sather H, Navara C, Nachman J, et al.
Clin Cancer Res
. 1999 Sep;
5(8):2112-20.
PMID: 10473095
Ikaros, a zinc finger-containing DNA-binding protein, is required for normal lymphocyte development. Germ-line mutant mice that express only non-DNA binding dominant-negative "leukemogenic" Ikaros isoforms lacking critical NH2-terminal zinc fingers develop...
17.
Uckun F, Nachman J, Sather H, Sensel M, Kraft P, Steinherz P, et al.
Leuk Lymphoma
. 1999 Apr;
33(1-2):101-6.
PMID: 10194126
Children with Philadelphia (Ph) chromosome positive (+) acute lymphoblastic leukemia (ALL) represent a subgroup at very high risk for treatment failure. This study included 1322 children enrolled between 1988 and...
18.
Reaman G, Sposto R, Sensel M, Lange B, Feusner J, Heerema N, et al.
J Clin Oncol
. 1999 Mar;
17(2):445-55.
PMID: 10080584
Purpose: Infants represent a very poor risk group for acute lymphoblastic leukemia (ALL). We report treatment outcome for such patients treated with intensive therapy on consecutive Children's Cancer Group (CCG)...
19.
Uckun F, Waurzyniak B, Sather H, Sensel M, Chelstrom L, Nachman J, et al.
Leuk Lymphoma
. 1999 Feb;
32(5-6):475-87.
PMID: 10048420
Contemporary intensive therapies are effective for the majority of pediatric T-lineage acute lymphoblastic leukemia (ALL) patients, thus current challenge is to identify patients who may benefit from alternative treatment modalities....
20.
Uckun F, Nachman J, Sather H, Sensel M, Kraft P, Steinherz P, et al.
Cancer
. 1998 Nov;
83(9):2030-9.
PMID: 9806664
Background: Children with Philadelphia (Ph) chromosome positive (+) acute lymphoblastic leukemia (ALL) represent a subgroup at very high risk for treatment failure. In this report, the authors assessed the outcome...