P G McCaffrey
Overview
Explore the profile of P G McCaffrey including associated specialties, affiliations and a list of published articles.
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24
Citations
1095
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0
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Recent Articles
1.
Costantini L, Chaturvedi P, Armistead D, McCaffrey P, Deacon T, Isacson O
Neurobiol Dis
. 1998 Sep;
5(2):97-106.
PMID: 9746907
Protection or regeneration of the dopaminergic (DA) system would be of significant therapeutic value for Parkinson's disease. Immunophilin ligands, such as FK506, can produce neurotrophic effects in vitro and in...
2.
McCaffrey P, Newsome D, Fibach E, Yoshida M, Su M
Blood
. 1997 Sep;
90(5):2075-83.
PMID: 9292546
The short-chain fatty acid butyrate has been shown to elevate fetal hemoglobin (HbF) by inducing expression of the gamma-globin gene. Regulation of gene expression by butyrate is thought to proceed...
3.
Wilson K, McCaffrey P, Hsiao K, Pazhanisamy S, Galullo V, Bemis G, et al.
Chem Biol
. 1997 Jun;
4(6):423-31.
PMID: 9224565
Background: The p38 mitogen-activated protein (MAP) kinase regulates signal transduction in response to environmental stress. Pyridinylimidazole compounds are specific inhibitors of p38 MAP kinase that block the production of the...
4.
Wilson K, Fitzgibbon M, Caron P, Griffith J, Chen W, McCaffrey P, et al.
J Biol Chem
. 1996 Nov;
271(44):27696-700.
PMID: 8910361
p38 mitogen-activated protein kinase is activated by environmental stress and cytokines and plays a role in transcriptional regulation and inflammatory responses. The crystal structure of the apo, unphosphorylated form of...
5.
Luo C, Burgeon E, Carew J, McCaffrey P, Badalian T, Lane W, et al.
Mol Cell Biol
. 1996 Jul;
16(7):3955-66.
PMID: 8668213
Transcription factors of the NFAT family play a key role in the transcription of cytokine genes and other genes during the immune response. We have identified two new isoforms of...
6.
Wang D, McCaffrey P, Rao A
Ann N Y Acad Sci
. 1995 Sep;
766:182-94.
PMID: 7486655
No abstract available.
7.
McCaffrey P, Goldfeld A, Rao A
J Biol Chem
. 1994 Dec;
269(48):30445-50.
PMID: 7982959
The tumor necrosis factor-alpha (TNF alpha) gene is an immediate early gene in activated T cells, in that it is rapidly induced without a requirement for protein synthesis. Maximal induction...
8.
McCaffrey P, Kim P, Sen R, Rao A
Nucleic Acids Res
. 1994 Jun;
22(11):2134-42.
PMID: 8029023
We have investigated the characteristics of IL2R alpha gene induction in untransformed murine T cells. Induction of IL2R alpha mRNA by TCR/CD3 ligands in a murine T cell clone and...
9.
Jain J, Nalefski E, McCaffrey P, Johnson R, Spiegelman B, Papaioannou V, et al.
Mol Cell Biol
. 1994 Mar;
14(3):1566-74.
PMID: 8114694
The ubiquitous transcription factors Fos and Jun are rapidly induced in T cells stimulated through the T-cell antigen receptor and regulate transcription of cytokines, including interleukin 2, in activated T...
10.
Rooney J, Hodge M, McCaffrey P, Rao A, Glimcher L
EMBO J
. 1994 Feb;
13(3):625-33.
PMID: 8313907
Murine T helper cell clones are classified into two distinct subsets, T helper 1 (Th1) and T helper 2 (Th2), on the basis of cytokine secretion patterns. Th1 clones produce...