P G Corn
Overview
Explore the profile of P G Corn including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
1651
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0
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Recent Articles
1.
Shah A, Kotecha R, Lemke E, Chandramohan A, Chaim J, Msaouel P, et al.
Eur J Cancer
. 2019 May;
114:67-75.
PMID: 31075726
Background: Immune checkpoint inhibitors (ICIs) are being increasingly utilised in the front-line (1L) setting of metastatic clear-cell renal cell carcinoma (mccRCC). Limited data exist on responses and survival on second-line...
2.
Jonasch E, Hasanov E, Corn P, Moss T, Shaw K, Stovall S, et al.
Ann Oncol
. 2017 Jan;
28(4):804-808.
PMID: 28049139
Background: Activation of the phosphoinisitide-3 kinase (PI3K) pathway through mutation and constitutive upregulation has been described in renal cell carcinoma (RCC), making it an attractive target for therapeutic intervention. We...
3.
Karanika S, Karantanos T, Li L, Corn P, Thompson T
Oncogene
. 2014 Aug;
34(22):2815-22.
PMID: 25132269
DNA damage response (DDR) includes the activation of numerous cellular activities that prevent duplication of DNA lesions and maintain genomic integrity, which is critical for the survival of normal and...
4.
Karantanos T, Corn P, Thompson T
Oncogene
. 2013 Jun;
32(49):5501-11.
PMID: 23752182
Prostate cancer is the second-leading cause of cancer-related mortality in men in Western societies. Androgen receptor (AR) signaling is a critical survival pathway for prostate cancer cells, and androgen-deprivation therapy...
5.
Som A, Tu S, Liu J, Wang X, Qiao W, Logothetis C, et al.
Br J Cancer
. 2012 Oct;
107(9):1547-53.
PMID: 23033003
Background: The bone-forming metastases of prostate cancer result from complex stromal-epithelial interactions within the tumour microenvironment. Autocrine-paracrine signalling pathways between prostate cancer epithelial cells, osteoblasts, and osteoclasts stimulate aberrant bone...
6.
Richey S, Culp S, Jonasch E, Corn P, Pagliaro L, Tamboli P, et al.
Ann Oncol
. 2010 Dec;
22(5):1048-1053.
PMID: 21115604
Background: Cytoreductive nephrectomy (CN) became a standard procedure in metastatic renal cell carcinoma (mRCC) in the immunotherapy era. Historically, median overall survival (OS) of patients treated with interferon alpha (IFN-α)...
7.
Corn P, Heath E, Heitmiller R, Fogt F, Forastiere A, Herman J, et al.
Clin Cancer Res
. 2001 Sep;
7(9):2765-9.
PMID: 11555590
Purpose: E-cadherin, a M(r) 120,000 transmembrane glycoprotein, mediates calcium-dependent intercellular adhesion that is essential for normal tissue homeostasis. Loss of E-cadherin occurs in a variety of epithelial tumors and is...
8.
Nicholson S, Okby N, Khan M, Welsh J, McMenamin M, Travis W, et al.
Cancer Res
. 2001 Jul;
61(14):5636-43.
PMID: 11454718
Overexpression of E2F-1 induces apoptosis by both a p14ARF-p53- and a p73-mediated pathway. p14ARF is the alternate tumor suppressor product of the INK4a/ARF locus that is inactivated frequently in lung...
9.
Esteller M, Corn P, Baylin S, Herman J
Cancer Res
. 2001 Apr;
61(8):3225-9.
PMID: 11309270
We are in an era where the potential exists for deriving comprehensive profiles of DNA alterations characterizing each form of human cancer. Such profiles would provide invaluable insight into mechanisms...
10.
Esteller M, Cordon-Cardo C, Corn P, Meltzer S, Pohar K, Watkins D, et al.
Cancer Res
. 2001 Apr;
61(7):2816-21.
PMID: 11306450
The INK4a/ARF locus encodes two distinct tumor suppressors, p16INK4a and p14ARF. Although the contribution of p16INK4a to human tumorigenesis through point mutation, deletion, and hypermethylation has been widely documented, little...