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P F Vaughan

Explore the profile of P F Vaughan including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 383
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Recent Articles
1.
Smith I, Boyle J, Vaughan P, Pearson H, Peers C
J Neurochem . 2001 Nov; 79(4):877-84. PMID: 11723180
Microfluorimetric measurements of intracellular calcium ion concentration [Ca(2+)](i) were employed to examine the effects of chronic hypoxia (2.5% O(2), 24 h) on Ca(2+) stores and capacitative Ca(2+) entry in human...
2.
Ramsden M, Plant L, Webster N, Vaughan P, Henderson Z, Pearson H
J Neurochem . 2001 Nov; 79(3):699-712. PMID: 11701773
The effects of amyloid beta protein on voltage-gated K(+) channel currents were studied using the whole-cell patch-clamp technique. The 1-40 amino acid form of amyloid beta protein was applied to...
3.
Webster N, Vaughan P, Peers C
Brain Res Mol Brain Res . 2001 Apr; 89(1-2):50-7. PMID: 11311975
The effects of chronic hypoxia (2.5% O(2), 24 h) on [3H]noradrenaline ([3H]NA) release evoked from human neuroblastoma SH-SY5Y cells by depolarisation and by activation of muscarinic receptors was investigated. Depolarization...
4.
Hartness M, Wade J, Walker J, Vaughan P
Eur J Neurosci . 2001 Mar; 13(5):925-34. PMID: 11264665
The aim of this study was to investigate a possible role of the myristoylated alanine-rich C kinase substrate (MARCKS) in the mechanism of noradrenaline uptake and release in the human...
5.
Roberts D, Khan N, McDonald R, Webster N, Peers C, Vaughan P
Brain Res Mol Brain Res . 2001 Feb; 87(1):81-91. PMID: 11223162
The aim of this study was to obtain further understanding of the mechanism by which activation of muscarinic M(1) receptors inhibits K(+)-evoked noradrenaline (NA) release in the human neuroblastoma SH-SY5Y....
6.
Partoens P, Slembrouck D, De Busser H, Vaughan P, Van Dessel G, De Potter W, et al.
Subcell Biochem . 2000 May; 34:323-78. PMID: 10808338
No abstract available.
7.
Vaughan P, Walker J, Peers C
Mol Neurobiol . 1999 Mar; 18(2):125-55. PMID: 10065877
The effect of protein kinase C (PKC) on the release of neurotransmitters from a number preparations, including sympathetic nerve endings, brain slices, synaptosomes, and neuronally derived cell lines, is considered....
8.
Danks K, Wade J, Batten T, Walker J, Ball S, Vaughan P
Brain Res Mol Brain Res . 1999 Feb; 64(2):236-45. PMID: 9931495
Our previous studies have shown that noradrenaline release is enhanced by activation of protein kinase Calpha in SH-SY5Y cells. In the present study, we report that activation of protein kinase...
9.
Ou X, Partoens P, Wang J, Walker J, Danks K, Vaughan P, et al.
Int J Mol Med . 1998 Dec; 1(1):105-12. PMID: 9852206
Sucrose gradient centrifugation combined with electron microscopy revealed that undifferentiated SH-SY5Y cells contain predominantly one population of noradrenaline containing vesicles, i.e. large dense cored vesicles. These vesicles have been purified...
10.
Wade J, Vaughan P, Peers C
J Neurochem . 1998 Sep; 71(4):1482-9. PMID: 9751181
We have used the human sympathetic neuronal line SH-SY5Y to investigate the effects of hypoxia on noradrenaline (NA) release evoked by either raised [K+]o (100 mM) or the nicotinic acetylcholine...