P F Robbins
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Explore the profile of P F Robbins including associated specialties, affiliations and a list of published articles.
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51
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2694
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Recent Articles
11.
Irvine K, Parkhurst M, Shulman E, Tupesis J, Custer M, Touloukian C, et al.
Cancer Res
. 1999 Jun;
59(11):2536-40.
PMID: 10363968
To study the induction of anti-"self" CD8+ T-cell reactivity against the tumor antigen gp100, we used a mouse transgenic for a chimeric HLA-A*0201/H-2 Kb molecule (A2/Kb). We immunized the mice...
12.
Clay T, Custer M, McKee M, Parkhurst M, Robbins P, Kerstann K, et al.
J Immunol
. 1999 Feb;
162(3):1749-55.
PMID: 9973438
In a recent clinical trial, HLA-A2+ melanoma patients were vaccinated with a peptide derived from the melanoma Ag gp100, which had been modified at the second position (g9-209 2M) to...
13.
Kawakami Y, Robbins P, Wang X, Tupesis J, Parkhurst M, Kang X, et al.
J Immunol
. 1998 Dec;
161(12):6985-92.
PMID: 9862734
To isolate melanoma Ags recognized by T cells, cDNA libraries made from melanoma cell lines were screened with four CTLs derived from tumor infiltrating lymphocytes (TIL) that were able to...
14.
Wang R, Wang X, Johnston S, Zeng G, Robbins P, Rosenberg S
Cancer Res
. 1998 Aug;
58(16):3519-25.
PMID: 9721852
A new retroviral system has been developed for the generation of a cDNA library and the functional cloning of tumor antigens. These retroviral vectors contain a cytomegalovirus promoter in the...
15.
Kawakami Y, Robbins P, Wang R, Parkhurst M, Kang X, Rosenberg S
J Immunother
. 1998 Jul;
21(4):237-46.
PMID: 9672845
Clinical observations in the interleukin (IL) 2-based immunotherapies suggest that T cells play a central role in the rejection of melanoma. Using cDNA expression cloning, we have isolated genes encoding...
16.
Robbins P, Li Y, Fitzgerald E, Kawakami Y, Rosenberg S
J Immunol
. 1997 Jul;
159(1):303-8.
PMID: 9200467
Recent studies have characterized a number of the Ags that are recognized by melanoma-reactive T cells. Although the majority of tumor Ags appear to represent nonmutated gene products, a variety...
17.
Kawakami Y, Battles J, Kobayashi T, Ennis W, Wang X, Tupesis J, et al.
J Immunol Methods
. 1997 Mar;
202(1):13-25.
PMID: 9075767
Recombinant human MART-1 protein was produced by bacterial and baculoviral-insect cell expression systems. By immunization with bacterial MBP-MART-1 fusion protein or MBP cleaved MART-1 protein, a rabbit polyclonal and two...
18.
Bloom M, Robbins P, Li Y, Rosenberg S, Yang J
J Exp Med
. 1997 Feb;
185(3):453-9.
PMID: 9053445
Recently, major advances have been made in the identification of antigens from human melanoma which are recognized by T cells. In spite of this, little is known about the optimal...
19.
Kang X, Robbins P, Fitzgerald E, Wang R, Rosenberg S, Kawakami Y
Cancer Res
. 1997 Jan;
57(2):202-5.
PMID: 9000554
Several epitopes in the human melanoma antigens recognized by HLA-A2-restricted CTLs have a relatively low MHC-binding affinity and as a result may be expressed at very low densities on the...
20.
Robbins P, Kawakami Y
Curr Opin Immunol
. 1996 Oct;
8(5):628-36.
PMID: 8902387
The ability of tumor-reactive T cells to mediate in vivo tumor regression has been demonstrated in murine tumor models and by the clinical responses to adoptive immunotherapy with tumor-infiltrating lymphocytes...