P F Piguet
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Explore the profile of P F Piguet including associated specialties, affiliations and a list of published articles.
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106
Citations
3142
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Recent Articles
1.
Libura J, Bettens F, Radkowski A, Tiercy J, Piguet P
Eur Respir J
. 2002 May;
19(5):912-8.
PMID: 12030733
In some patients, chemotherapy (CHT) of cancer can result in pulmonary inflammation and fibrosis, eventually leading to respiratory insufficiency. As animal studies have underlined the importance of major histocompatibility complex...
2.
Piguet P, Vesin C, Da Laperousaz C, Rochat A
Hematol J
. 2002 Mar;
1(3):199-205.
PMID: 11920190
Introduction: Plasminogen activators (PA) and plasmin are known to affect platelets but little is known of their role in platelet kinetics. We took advantage of genetically deficient mice to explore...
3.
Piguet P, Kan C, Vesin C
Apoptosis
. 2002 Feb;
7(2):91-8.
PMID: 11865192
Infection of mice with Plasmodium Berghei Anka (PbA) leads to a thrombocytopenia, due to a reduced platelet life span, eventually associated with a syndrome of severe or cerebral malaria (CM)....
4.
Piguet P, Da Laperrousaz C, Vesin C, Donati Y
Dev Immunol
. 2002 Jan;
8(3-4):183-91.
PMID: 11785668
Incidence of apoptosis was investigated in the spleen and lymph nodes of +/+, CD18 -/- and urokinase receptor (uPAR, CD87) -/- mice, untreated or Plasmodium Berghei Anka (PbA) infected. In...
5.
Barazzone-Argiroffo C, Muzzin P, Donati Y, Kan C, Aubert M, Piguet P
Am J Physiol Lung Cell Mol Physiol
. 2001 Oct;
281(5):L1150-6.
PMID: 11597906
Leptin, a cytokine involved in the regulation of food intake, has been reported to be decreased in lung diseases such as chronic obstructive pulmonary disease and cystic fibrosis and increased...
6.
Piguet P, Kan C, Vesin C, Rochat A, Donati Y, Barazzone C
Am J Pathol
. 2001 Aug;
159(2):733-42.
PMID: 11485931
We explored the role of CD40-CD40L (CD154) in the severe malaria elicited by Plasmodium berghei anka infection in mice. Mortality was >90% by day 8 after infection in +/+ mice,...
7.
Piguet P, Vesin C, Rochat A
Eur J Cell Biol
. 2001 Apr;
80(2):171-7.
PMID: 11302522
We explored the role of CD18 (beta2 integrin) in platelet physiology, using mice genetically deficient in CD18 (CD18 -/-), or its main ligand CD54 (ICAM-1, CD54 -/-). CD18 and CD11a...
8.
Piguet P, Da Laperrousaz C, Vesin C, Tacchini-Cottier F, Senaldi G, Grau G
Infect Immun
. 2000 Jun;
68(7):3822-9.
PMID: 10858190
We explored the role of urokinase and tissue-type plasminogen activators (uPA and tPA), as well as the uPA receptor (uPAR; CD87) in mouse severe malaria (SM), using genetically deficient (-/-)...
9.
Favre N, Da Laperousaz C, Ryffel B, Weiss N, Imhof B, Rudin W, et al.
Microbes Infect
. 2000 Jan;
1(12):961-8.
PMID: 10617927
In susceptible mouse strains, infection of mice with Plasmodium berghei ANKA (PbA) results in a lethal complication, cerebral malaria. Cerebral malaria is due to the immune response induced by the...
10.
Piguet P, Vesin C, Donati Y, Tacchini-Cottier F, Belin D, Barazzone C
Circulation
. 1999 Jun;
99(25):3315-21.
PMID: 10385508
Background: Urokinase plasminogen activator receptor (uPAR, CD87) is a widely distributed 55-kD, glycoprotein I-anchored surface receptor. On binding of its ligand uPA, it is known to increase leukocyte adhesion and...