P E Nielsen
Overview
Explore the profile of P E Nielsen including associated specialties, affiliations and a list of published articles.
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335
Citations
4361
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Recent Articles
1.
Gils C, Eckhardt M, Nielsen P, Nybo M
Case Rep Pediatr
. 2016 Sep;
2016:2519498.
PMID: 27635272
Background. Congenital chloride diarrhea (CCD) is an autosomal recessive disorder caused by mutations in the genes encoding the intestinal Cl(-)/HCO3 (-) exchanger and is clinically characterized by watery, profound diarrhea,...
2.
Zhang Q, March G, Noel V, Piro B, Reisberg S, Tran L, et al.
Biosens Bioelectron
. 2011 Dec;
32(1):163-8.
PMID: 22186165
We report a signal-on, label-free and reagentless electrochemical DNA biosensor, based on a mixed self-assembled monolayer of thiolated hydroxynaphthoquinone and thiolated oligonucleotide. Electrochemical changes resulting from hybridization were evidenced with...
3.
Nielsen P, Bell G, Lassen N
Scand J Clin Lab Invest
. 2010 May;
29(4):371-9.
PMID: 20465478
The systolic blood pressure on the finger, toe, and ankle has been measured by a strain gauge technique in 10 normal subjects aged 17-31 years and 14 normal subjects aged...
4.
Reisberg S, Dang L, Nguyen Q, Piro B, Noel V, Nielsen P, et al.
Talanta
. 2008 Jul;
76(1):206-10.
PMID: 18585264
An electrochemical hybridization biosensor based on peptide nucleic acid (PNA) probe is presented. PNA were attached covalently onto a quinone-based electroactive polymer. Changes in flexibility of the PNA probe strand...
5.
6.
Rasmussen H, Petersson B, Nielsen P, Liljefors T, Kastrup J
J Biomol Struct Dyn
. 2003 Dec;
21(4):495-502.
PMID: 14692794
The X-ray structure of a self-complementary PNA hexamer (H-CGTACG-L-Lys-NH(2)) has been determined to 2.35 A resolution. The introduction of an L-lysine moiety has previously been shown to induce a preferred...
7.
Behrens C, Harrit N, Nielsen P
Bioconjug Chem
. 2001 Nov;
12(6):1021-7.
PMID: 11716695
The synthesis of a new versatile "Hoechst 33258-like" Boc-protected amino acid building block for peptide synthesis is described. It is demonstrated that this new ligand is an effective mimic of...
8.
Kushon S, Jordan J, Seifert J, Nielsen H, Nielsen P, Armitage B
J Am Chem Soc
. 2001 Nov;
123(44):10805-13.
PMID: 11686681
The binding of a series of PNA and DNA probes to a group of unusually stable DNA hairpins of the tetraloop motif has been observed using absorbance hypochromicity (ABS), circular...
9.
Kambhampati D, Nielsen P, Knoll W
Biosens Bioelectron
. 2001 Oct;
16(9-12):1109-18.
PMID: 11679296
Plasmon surface polaritons, resonantly excited in the Kretschmann format, are used to enhance the fluorescence emission of chromophore-labeled oligonucleotides (15mers) binding to surface-attached (via biotin-streptavidin linkages) complement catcher probes. A...
10.
Nielsen P, Egholm M
Bioorg Med Chem
. 2001 Sep;
9(9):2429-34.
PMID: 11553484
Mixed pyrimidine-purine peptide nucleic acids (PNAs) composed of thymines and guanines are shown to form a PNA(2)-DNA triplex with Watson-Crick complementary adenine-cytosine oligonucleotides and to bind complementary adenine-cytosine targets in...