P E Dekkers
Overview
Explore the profile of P E Dekkers including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
307
Followers
0
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Recent Articles
1.
Juffermans N, Dekkers P, Verbon A, Speelman P, van Deventer S, van der Poll T
Infect Immun
. 2001 Jul;
69(8):5182-5.
PMID: 11447203
Patients with tuberculosis had higher expression of monocyte urokinase receptor (uPAR) and CD11b than controls. In vitro, lipoarabinomannan and lipopolysaccharide (LPS) from Escherichia coli shared the ability to enhance uPAR...
2.
de Jonge E, Dekkers P, Creasey A, Hack C, Paulson S, Karim A, et al.
J Infect Dis
. 2001 May;
183(12):1815-8.
PMID: 11372037
Activation of coagulation induces a proinflammatory response in in vitro and animal experiments. Inhibition of the tissue factor-dependent pathway of coagulation inhibits cytokine release and prevents death in gram-negative sepsis...
3.
Olszyna D, de Jonge E, Dekkers P, van Deventer S, van der Poll T
Infect Immun
. 2001 Mar;
69(4):2736-8.
PMID: 11254644
Erythrocytes express the Duffy antigen receptor for chemokines. Endotoxin injection into humans induced high levels of interleukin-8 (IL-8), growth-related oncogene alpha, and monocyte chemoattractant protein 1 in circulating erythrocytes. IL-8...
4.
Verbon A, Dekkers P, Ten Hove T, Hack C, Pribble J, Turner T, et al.
J Immunol
. 2001 Feb;
166(5):3599-605.
PMID: 11207321
CD14 is a receptor for cell wall components of Gram-negative and Gram-positive bacteria that has been implicated in the initiation of the inflammatory response to sepsis. To determine the role...
5.
Juffermans N, Paxton W, Dekkers P, Verbon A, de Jonge E, Speelman P, et al.
Blood
. 2000 Oct;
96(8):2649-54.
PMID: 11023494
Concurrent infections in patients with human immunodeficiency virus (HIV) infection stimulate HIV replication. Chemokine receptors CXCR4 and CCR5 can act as HIV coreceptors. The authors hypothesized that concurrent infection increases...
6.
Juffermans N, Dekkers P, Peppelenbosch M, Speelman P, van Deventer S, van der Poll T
J Infect Dis
. 2000 Aug;
182(3):888-94.
PMID: 10950785
The chemokine receptors CXCR1 and CXCR2 critically determine the functional properties of granulocytes. To obtain insight in the regulation of these receptors during infection, CXCR expression was determined on blood...
7.
Franco R, de Jonge E, Dekkers P, Timmerman J, Spek C, van Deventer S, et al.
Blood
. 2000 Jul;
96(2):554-9.
PMID: 10887118
Triggering of the tissue factor (TF)-dependent coagulation pathway is considered to underlie the generation of a procoagulant state during endotoxemia. To determine the in vivo pattern of monocytic TF messenger...
8.
Dekkers P, Juffermans N, Hove T, de Jonge E, van Deventer S, van der Poll T
J Infect Dis
. 2000 Jun;
181(6):2067-70.
PMID: 10837195
Granulocyte colony-stimulating factor (G-CSF) is considered an important mediator of host defense against infection, and recombinant G-CSF is administered to patients with various infections. G-CSF binds to a specific receptor...
9.
Dekkers P, Ten Hove T, Lauw F, Koene H, Lumley P, van Deventer S, et al.
Infect Immun
. 2000 Apr;
68(5):3036-9.
PMID: 10769011
Metalloproteinases have been implicated in the cleavage of a number of cell surface immune receptors. Oral administration of the metalloproteinase inhibitor GI5402 attenuated the release of soluble CD27 and CD16...
10.
Dekkers P, Ten Hove T, Te Velde A, van Deventer S, van der Poll T
Infect Immun
. 2000 Mar;
68(4):2156-60.
PMID: 10722614
The receptor for urokinase-type plasminogen activator (uPAR) (CD87) plays an important role in leukocyte adhesion and migration. To assess the effect of endotoxin on cellular uPAR, uPAR expression was determined...